80096-38-4Relevant academic research and scientific papers
Metal-Free C–S Bond Cleavage to Access N-Substituted Acrylamide and β-Aminopropanamide
Yang, Ke,Li, Yi,Ma, Zhiyan,Tang, Long,Yin, Yue,Zhang, Hao,Li, Zhengyi,Sun, Xiaoqiang
supporting information, p. 5812 - 5814 (2019/08/27)
Metal-free and Selectfluor-mediated C–S bond cleavage is described. This novel strategy provides a facile and efficient method to access important N-substituted acrylamide and β-aminopropanamide derivatives with good functional group tolerance and yields.
THE CHEMISTRY OF LACTIM ETHERS. V. REACTION OF LACTIM THIOETHERS WITH β-AMINOESTERS
Takahata, Hiroki,Tomoguchi, Akira,Yamazaki, Takao
, p. 2525 - 2530 (2007/10/02)
Reaction of a cyclic β-aminoester such as 2-ethoxycarbonylmethylpiperidine (5) with the lactim thioethers 1b and 1c gave a 10-membered cyclic diamide (7) and an 11-membered ring compound (9), respectively.On the other hand, though acyclic β-aminoesters (6) reacted with 1 to afford methyl 3-methylthiopropionate (11), N-alkyl 3-methylthiopropionamide (12), lactams (13), and amidines (14), no cyclic diamide was obtained.Keywords: - lactim thioethers; cyclic β-aminoesters; acyclic β-aminoesters; cyclic diamide; medium-ring; methyl 3-methylthiopropionate; N-alkyl 3-methylthiopionamide; amidines; lactams; β-lactmams
