80109-83-7Relevant academic research and scientific papers
An efficient route to quinoline-2-carboxylates via a rhodium-catalyzed oxidative [5+1] annulation of 2-vinylanilines with α-diazocarbonyl compounds
Wang, Cong,Ding, Qiuping,Zheng, Qiang,Bao, Ping,Peng, Yiyuan
, p. 348 - 353 (2017/12/11)
A novel rhodium-catalyzed oxidative [5 + 1] annulation of 2-vinylanilines with α-diazocarbonyl compounds for the construction of quinoline-2-carboxylate derivatives has been developed. A series of functional groups such as methyl, methoxy, fluoro, chloro, bromo, cyano, and even thienyl substituents were tolerated well. This methodology has the potential for use in the pharmaceutical industry.
