80117-82-4

Basic information

• Product Name: 1-(β-D-Ribofuranosyl)-3-thiocarbamoyl-4-methylmercaptopyrazolo<3,4-d>parimidine
• Synonyms: 1-(β-D-Ribofuranosyl)-3-thiocarbamoyl-4-methylmercaptopyrazolo<3,4-d>parimidine
• CAS NO: 80117-82-4
• Molecular Weight: 357.414
• Mol File: 80117-82-4.mol

Chemical Properties

• CAS DataBase Reference: 1-(β-D-Ribofuranosyl)-3-thiocarbamoyl-4-methylmercaptopyrazolo<3,4-d>parimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(β-D-Ribofuranosyl)-3-thiocarbamoyl-4-methylmercaptopyrazolo<3,4-d>parimidine(80117-82-4)
• EPA Substance Registry System: 1-(β-D-Ribofuranosyl)-3-thiocarbamoyl-4-methylmercaptopyrazolo<3,4-d>parimidine(80117-82-4)

Safety Data

• Hazardous Substances Data: 80117-82-4(Hazardous Substances Data)

Upstream product

• 54385-49-8 5-amino-1H-pyrazole-3,4-dicarbonitrile 

Relevant articles and documents

SYNTHESIS OF 3-SUBSTITUTED 4-METHYLMERCAPTO- AND 4-AMINOPYRAZOLOPYRIMIDINES AND THEIR RIBOSIDES

3-Cyano-4-methylmercaptopyrazolopyrimidine, fusion of which with 1,2,3,5-tetra-O-acetyl-β-D-ribofuranose gave its per-O-acetylated 1-β-D-ribofuranoside in 61percent yield, was synthesized from 3,4-dicyano-5-aminopyrazole.O-Deacetylation of the per-O-acetylated 1-β-D-ribofuranoside was carried out by the action of 1percent HCl in methanol. New pyrazolopyrimidines were obtained by the reaction of 3-cyano-4-methylmercaptopyrazolopyrimidine and its 1-riboside, as well as 3-cyano-4-aminopyrazolopyrimidine, with a number of nucleophilic reagents.The cytotoxic activities of the compounds obtained were studied.