80124-30-7

Basic information

• Product Name: 2-cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, oxime, (5S)-
• CAS NO: 80124-30-7
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.2322
• Mol File: 80124-30-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 279.009°C at 760 mmHg
• Flash Point: 164.104°C
• Density: 1.006g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: 2-cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, oxime, (5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, oxime, (5S)-(80124-30-7)
• EPA Substance Registry System: 2-cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, oxime, (5S)-(80124-30-7)

Safety Data

• Hazardous Substances Data: 80124-30-7(Hazardous Substances Data)

Upstream product

• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 

Downstream Products

• 69658-72-6 p-mentha-6,8-dien-2-on-(O-acetyl oxime ) 
• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 619-01-2 (1R,2R,4R)-dihydrocarveol 
• 53796-79-5 (1R,4S)-isodihydrocarvone 
• 53796-80-8 (1R,2S,4S)-(-)-neodihydrocarveol 
• 53567-68-3 N_.N'-Biscaroylthioharnstoff 
• 53567-65-0 Caroylisothiocyanat 
• 62311-60-8 N-p-mentha-6,8-dien-2-yl-benzamide 
• 53567-64-9 carvylamine 
• 76190-11-9 N-(1-ethylpropyl)isocarvomenthylamine 
• 76184-02-6 N-(1-ethylpropyl)neocarvomenthylamine 
• 76190-12-0 N-(1-ethylpropyl)neoisocarvomenthylamine 
• 76184-01-5 N-(1-ethylpropyl)carvomenthylamine 
• 76184-07-1 Cyclopentyl-((1R,2R,5S)-5-isopropyl-2-methyl-cyclohexyl)-amine 

Relevant articles and documents

Synthesis of nitrogen-containing monoterpenoids with antibacterial activity

Incorporation of the Beckmann rearrangement into the presented research resulted in the formation of nitrogen-containing terpenoid derivatives originating from naturally occurring compounds. Both starting monoterpenes and obtained derivatives were subjected to estimation of their antibacterial potential. In the presented study, Staphylococcus aureus was the most sensitive to examined compounds. The Minimal Inhibitory Concentration (MIC) experiments performed on S. aureus demonstrated that the (?)-menthone oxime (?)-8 and (+)-pulegone oxime (+)-13 had the best antibacterial activity among the tested derivatives and starting compounds. Their MIC90 value was 100 μg/mL. The obtained derivatives were also evaluated for their inhibitory activity against bacterial urease. Among the tested compounds, three active inhibitors were found–oxime 14 and lactams (?)-15 and 16 limited the activity of Sporosarcina pasteurii urease with Ki values of 174.3 μM, 43.0 μM and 4.6 μM, respectively. To our knowledge, derivative 16 is the most active antiureolytic lactam described to date.

THE BIOTRANSFORMATION OF CARVOXIME AND DEHYDROCARVOXIME WITH CELL SUSPENSION CULTURES OF NICOTIANA TABACUM

In newly initiated cell suspension cultures of Nicotiana tabacum (4R)-(-)-and (4S)-(+)-carvoximes and (1S,4R)-(+)-dihydrocarvoxime were hydrolysed to the corresponding ketones and then the resultant ketones were reduced to the corresponding alcohols.Key words: Nicotiana tabacum; Solanaceae; tissue culture; biotransformation; hydrolysis; carvoxime; dihydrocavoxime.