801294-04-2Relevant academic research and scientific papers
Silylstannylation of highly functionalized acetylenes. Synthesis of precursors for annulations via radical or heck reactions
Apte, Sandeep,Radetich, Branko,Shin, Seunghoon,RajanBabu
, p. 4053 - 4056 (2004)
(Chemical Equation Presented) Pd-catalyzed silylstannylation of acetylenes tolerates a variety of reactive functional groups (aldehydes, nonterminal acetylenes, epoxides, activated and unactivated olefins), providing easy access to precursors that can be
Titanium(III)-induced intramolecular radical cyclization of epoxyallene ethers: an efficient method for synthesis of multifunctional tetrahydrofurans
Xu, Lubin,Huang, Xian
, p. 500 - 503 (2008/04/13)
Ti(III)-mediated intramolecular free radical cyclization of epoxyallene ethers in an exo-mode was studied. The reaction afforded an efficient and highly regioselective method of synthetically important 3-vinyl-4-hydroxymethyl tetrahydrofurans.
A gold(I)-catalyzed intramolecular reaction of propargylic/homopropargylic alcohols with oxirane
Dai, Lun-Zhi,Shi, Min
supporting information; experimental part, p. 7011 - 7018 (2009/08/12)
The gold(I)-catalyzed cycloisomerization of epoxy alkynes in the presence of a nucleophile is an efficient protocol to provide ketal skeletons with high stereoselectivity. An intramolecular reaction of propargylic/homopropargylic alcohols with oxirane to produce ketal/spiroketals in moderate yields under mild conditions has been reported. Moreover, the mechanism of this kind of reaction has been discussed on the basis of a series of control and 18O tracer experiments.
Gold(l)-catalyzed cascade cyclization reaction: Highly regio- and diastereoselective intermodular addition of water and alcohols to epoxy alkynes
Dai, Lun-Zhi,Qi, Ming-Juan,Shi, Yong-Ling,Liu, Xu-Guang,Shi, Min
, p. 3191 - 3194 (2008/02/11)
We have developed a novel access to ketal skeletons through a highly regio- and diastereoselective intermolecular addition of water and alcohols to alkynyl epoxides catalyzed by goid(l). This procedure involves a domino three-membered ring-opening, 6-exo-
