80174-58-9

Upstream product

• 1738-72-3 L-serine benzyl ester 
• 100-52-7 benzaldehyde 
• 60022-62-0 L-serine benzyl ester hydrochloride 

Downstream Products

• 1101847-10-2 C₆₆H₈₃NO₇ 
• 1415318-23-8 N-benzyl-2-(4-hydroxybenzamido)benzylacrylate 
• 1415318-29-4 N-benzyl-3-(benzyloxycarbonyl)-2-azaspiro[4.5]dec-3,6,9-trien-1,8-dione 
• 1415318-30-7 C₁₇H₁₃NO₄ 

Relevant academic research and scientific papers

A hypervalent iodine-mediated spirocyclization of 2-(4-hydroxybenzamido) acrylates - Unexpected formation of δ-spirolactones

On the way towards a new total synthesis of (S)-arogenate, a novel aryl-λ3-iodane-mediated oxidative spirocyclization of para-substituted phenol derivatives has been discovered. Starting from easy accessible 2-(4-hydroxybenzamido)acrylates we c

Beta-carbolines useful for treating inflammatory disease

This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.

BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE

This invention provides beta-carboline compounds of formula (I) wherein Ring A is a substituted pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl ring and R1, R2 and R3 are as described in the specification. The compounds are IKK-2 inhibitors that are useful for treating IKK-2 mediated diseases such as inflammatory diseases and cancer.