80174-65-8 Usage
General Description
2-[(2-chloroacetyl)amino]-3-hydroxy-propanoic acid, also known as chloramphenicol, is a broad-spectrum antibiotic used to treat various bacterial infections. It works by inhibiting bacterial protein synthesis, making it effective against a wide range of bacteria. Chloramphenicol is typically administered topically or orally and is used to treat conditions such as bacterial conjunctivitis, meningitis, and typhoid fever. However, due to its potential for serious side effects, including bone marrow suppression and aplastic anemia, its use is now limited and closely monitored. Chloramphenicol is classified as a last-resort treatment for serious infections that are resistant to other antibiotics.
Check Digit Verification of cas no
The CAS Registry Mumber 80174-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,7 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 80174-65:
(7*8)+(6*0)+(5*1)+(4*7)+(3*4)+(2*6)+(1*5)=118
118 % 10 = 8
So 80174-65-8 is a valid CAS Registry Number.
80174-65-8Relevant academic research and scientific papers
One-pot synthesis of phenylseleno N-acetyl α-amino acids: Supra-molecular self-assembling in organoselenium compounds
Parashiva Prabhu,Phadnis, Prasad P.,Wadawale, Amey,Priyadarsini, K. Indira,Jain, Vimal K.
, p. 140 - 147 (2013/10/01)
A convenient one-pot synthesis of phenylseleno N-acetyl α-amino acids, PhSeCH2C(O)NHC(R)COOH (R = H (1), Me (2), PhCH2 (3), 4-HOC6H4CH2 (4) and CH2OH (5)) is reported. These compounds have been characterized by microanalyses, UV-Vis, IR and NMR (1H, 13C, 77Se) spectroscopy. The molecular structures of [PhSeCH2CONHCH2COOH] (1), [PhSeCH2CONHCH(CH2C6H4OH-4)COOH] (4) and [PhSeCH2CONHCH(CH2OH)COOH] (5) have been established by X-ray diffraction analyses. These compounds are associated in the solid state through hydrogen bonding to give supra-molecular self-assembled structures. Free radical scavenging activity of these compounds has also been evaluated by DPPH assay.
