80177-93-1

Upstream product

• 33800-41-8 1L-1,2-anhydro-myo-inositol 
• 100-39-0 benzyl bromide 
• 317810-28-9 1L-1,6-di-O-allyl-chiro-inositol 
• 317810-29-0 1L-1,6-di-O-allyl-2,3,4,5-tetra-O-benzyl-chiro-inositol 
• 849550-89-6 2,3:4,5-di-O-(2',3'-dimethoxybutane-2',3'-diyl)-L-chiro-inositol 
• 38876-99-2 1L-chiro-inositol 
• 316806-88-9 1L-2,3,4,5-tetra-O-benzyl-chiro-inositol 

Downstream Products

• 80177-94-2 1L-(1,3/2,4)-1,2,3,4-Tetrakis(benzyloxy)-5-cyclohexen 

Relevant academic research and scientific papers

New syntheses of 1D- and 1L-1,2-anhydro-myo-inositol and assessment of their glycosidase inhibitory activities

The 1D and 1L enantiomers of 1,2-anhydro-myo-inositol (conduritol B epoxide) were synthesised from 1d-pinitol and 1l-quebrachitol, respectively, and their activities were compared in selected glycosidase inhibition assays. The 1d enantiomer was found to be the active isomer, functioning as an irreversible inhibitor of sweet almond β-D-glucosidase. Neither isomer was active against the α-D-glucosidase from Bacillus stearothermophilus or the β-D-galactosidase from Aspergillus oryzae. (C) 2000 Elsevier Science Ltd.

Cyclitol Reactions, IV. Synthesis of Enantiomeric Conduritols and Amino-Conduritols

The key-intermediate for all syntheses described in this paper is the 1-O-tosylate 7 of quebrachitol (1).This leads, via 8, to the 1L-conduritol B (5) and, via 13, to the 1L-conduritol F (17).Selective displacement of the equatorial tosyloxy group in comp