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(3Z)-3-[(4-chlorophenyl)methylidene]-5-phenylthiophen-2(3H)-one, also known as clofentezine, is a synthetic acaricide that is commonly used in agriculture to control the population of mites on crops. It is a thiophene compound characterized by its strong ovicidal and larvicidal properties, making it effective in targeting mite eggs and larvae.
Used in Agriculture:
Clofentezine is used as an acaricide for controlling mite populations on crops. It works by disrupting the mites' ability to molt and reproduce, ultimately leading to their death. However, there are concerns about its potential environmental impact and toxicity, leading to its restricted use and regulation in some countries.

80224-53-9

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80224-53-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 80224-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,2,2 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 80224-53:
(7*8)+(6*0)+(5*2)+(4*2)+(3*4)+(2*5)+(1*3)=99
99 % 10 = 9
So 80224-53-9 is a valid CAS Registry Number.

80224-53-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (3Z)-3-[(4-chlorophenyl)methylidene]-5-phenylthiophen-2-one

1.2 Other means of identification

Product number -
Other names 3-(4-chlorobenzylidene)-5-phenylthiophen-2-(3H)one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80224-53-9 SDS

80224-53-9Relevant academic research and scientific papers

Benzylidene-Thiolactone Rearrangement: Synthesis and Rearrangement of 5-Substituted 3-Benzylidene-4-thiolen-2-ones

Heindel, Ned D.,Conley, Richard A.,Minatelli, John A.,Boschelli, Diane Harris

, p. 3051 - 3053 (2007/10/02)

Condensation of 5-substituted 4-thiolen-2-ones (1) with aromatic aldehydes (2) in anhydrous ethanolic HCl generates the 3-benzylidene derivatives 3.These can be rearranged in base (benzylidene-thiolactone rearrangement) to 2,5-disubstituted thiophene-3-carboxylic acids (4, 5, or 6).

Improved Synthesis of 3-Aralkylidine-5-arylthiophen-2-(3H)ones

Miller, Gerald A.,Heindel, Ned D.,Minatelli, John A.

, p. 1253 - 1254 (2007/10/02)

3-Aralkylidene-5-arylthiophen-2-(3H)ones can be prepared in two steps from 4-aryl-4-oxobutanoic acids through the intermediacy of butenolides and thiophenones generated by the sequential action of acetic anhydride, sodium hydrosulfide and aromatic aldehyd

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