80251-75-8Relevant articles and documents
Practical synthesis of 5-substituted tetrazoles under microwave irradiation
Roh, Jaroslav,Artamonova, Tatjana V.,Vavrova, Katerina,Koldobskii, Grigorii I.,Hrabalek, Alexandr
, p. 2175 - 2178 (2009)
5-Substituted tetrazoles were prepared by treatment of nitriles with sodium azide and triethylammonium chloride in nitrobenzene in a microwave reactor. This practical method combines the advantages of previous procedures, including good-to-excellent yields, short reaction times, and easy isolation of the product. Moreover, sterically hindered tetrazoles, as well as those deactivated by electron-donating groups, can be prepared. Georg Thieme Verlag Stuttgart.