80277-06-1

Basic information

• Product Name: 7-chlorobenzo[c][1,2,5]oxadiazol-4-aMine
• Synonyms: 7-chlorobenzo[c][1,2,5]oxadiazol-4-aMine;4-Amino-7-chloro-2,1,3-benzoxadiazole
• CAS NO: 80277-06-1
• Molecular Formula: C₆H₄ClN₃O
• Molecular Weight: 169.56846
• Mol File: 80277-06-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-chlorobenzo[c][1,2,5]oxadiazol-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chlorobenzo[c][1,2,5]oxadiazol-4-aMine(80277-06-1)
• EPA Substance Registry System: 7-chlorobenzo[c][1,2,5]oxadiazol-4-aMine(80277-06-1)

Safety Data

• Hazardous Substances Data: 80277-06-1(Hazardous Substances Data)

Usage

General Description

7-Chlorobenzo[c][1,2,5]oxadiazol-4-amine is a chemical compound with the molecular formula C7H4ClN3O and a molecular weight of 175.58 g/mol. It is a chlorinated oxadiazole derivative that has potential applications in the field of organic synthesis, medicinal chemistry, and material science. 7-Chlorobenzo[c][1,2,5]oxadiazol-4-amine contains a benzene ring fused with an oxadiazole ring, and the presence of a chloro group at position 7 makes it a versatile building block for the synthesis of various biologically active molecules. 7-Chlorobenzo[c][1,2,5]oxadiazol-4-amine has been studied for its potential as an anticancer agent and has also been used in the development of fluorescent probes for biological imaging. Additionally, it can serve as a precursor for the synthesis of advanced materials with unique properties. However, its exact applications and potential uses in different fields are still under investigation.

Upstream product

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Relevant articles and documents

Rational design of NIR fluorescence probes for sensitive detection of viscosity in living cells

Developing near-infrared (NIR) fluorescence probes for detection of intracellular viscosity is still sufficiently challenging. In this work, three kinds of D-A-D type naphthyl and 2,1,3?benzoxadiazol hybrid NIR dyes functionalized with amino (NY1), N?methylamino (NY2) and N,N?dimethylamino (NY3) groups for intracellular micro-viscosity detection were designed and synthesized. All the probes exhibited very weak NIR emission in low viscosity environment and obvious fluorescence enhancement with the increased viscosity. Different substituent groups had a high impact on the photophysical properties and response sensitive of the probes to viscosity. The structure-property relationships were systematic investigated. The results showed that stronger electron-donating ability and larger steric effect of N,N?dimethylamino led to a narrower energy gap and more sensitive to viscosity environment. Therefore, NY3 exhibited higher signal noise ratio for viscosity detection and was successfully applied for imaging the changes of intracellular micro-viscosity. This work provides an efficient way to design powerful NIR fluorescence probes for viscosity detection.

Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans

The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds, and the immune modulation and modulation of cancer stem cell activity through administration of

DRUGS FOR INHIBITING P38 AND USES THEREOF

The present invention relates to compounds with a benzoxadiazolyl amine structure which are capable of inhibiting the activation or the biological activity of p38 mitogen-activated protein kinase (MAPK) and the use thereof in the treatment of a disease th