80283-06-3Relevant academic research and scientific papers
Ru-Catalyzed Chemo- And Enantioselective Hydrogenation of 2,4-Pentadien-1-ones: Synthesis of Chiral 2,4-Pentadien-1-ols
Li, Chengyang,Lu, Wenkui,Lu, Bin,Li, Wanfang,Xie, Xiaomin,Zhang, Zhaoguo
, p. 16086 - 16094 (2019/12/24)
The asymmetric hydrogenation of 2,4-pentadien-1-ones has been achieved by using trans-RuCl2[(R)-XylylSunPhos][(R)-Daipen] as a catalyst under basic conditions. This hydrogenation demonstrated exclusive C1-carbonyl selectivity, and thus the conjugated 2,4-diene motifs remained untouched, which provides a synthetically useful method for various chiral 2,4-pentadien-1-ols.
Construction of β to carbonyl stereogenic centres by asymmetric 1,4-addition of alkylzirconocenes to dienones and ynenones
Gao, Zhenbo,Fletcher, Stephen P.
supporting information, p. 3601 - 3604 (2018/04/12)
Copper-catalyzed asymmetric 1,4-addition of alkylzirconium species to linear α,β,γ,δ unsaturated dienones and ynenones is reported. A variety of alkyl nucleophiles are introduced with good yields and excellent regio- and enantio-selectivities to give tertiary carbon centres bearing multiple functional groups. The method is also applicable to an ynethioate with ee's over 96%.
A FACILE SYNTHESIS OF ο-SUBSTITUTED CONJUGATED POLYENONES VIA ARSONIUM SALT AND ITS APPLICATION TOWARDS THE SYNTHESIS OF NAVENONE A
Shi, Lilan,Xia, Wenjuan,Yang, Jianhua,Wen, Xueging,Huang, Y. Z.
, p. 2155 - 2158 (2007/10/02)
In the presence of K2CO3, a variety of aldehydes condensed with the arsonium bromide 8 at 0-3 deg C to give exclusively ο-substituted polyenones 1 in good yields, and the synthesis of navenone A was achieved by this procedure.
ω-BROMOALKAPOLYENYLMETHYL KETONES-I. REACTION OF 5-BROMO-3-PENTEN-2-ONE WITH TRIPHENYLPHOSPHINE
Font, J.,March, P. de
, p. 2391 - 2396 (2007/10/02)
The reaction of (E)-5-bromo-3-penten-2-one with triphenylphosphine affords a 3:1 mixture of two protomeric phosphonium salts: 4-oxo-2-pentenyltriphenylphosphonium bromide and 4-oxo-1-pentenyltriphenylphosphonium bromide, characterized by the 13C NMR spectrum of the mixture.However, the common phosphorane of these salts gives two condensation products with benzaldehyde, corresponding to α- and γ-condensation respectively.
