80283-63-2Relevant academic research and scientific papers
Iron-catalyzed regio- and stereoselective conjugate addition of aryl-grignard reagents to α,β,γ,δ-unsaturated sulfones and its synthetic application
Hata, Takeshi,Nakada, Takuya,Oh, Yun Taek,Hirone, Naoki,Urabe, Hirokazu
, p. 1736 - 1740 (2013)
The iron-catalyzed δ-addition of aryl-Grignard reagents to α,β,γ,δ-unsaturated sulfones proceeded in a regio- and stereoselective manner to give cis-4-aryl-2-alkenyl sulfones. Allylic alkylation of the resultant products was performed without isomerization of the cis-olefin to give cis-4-aryl-1,1-dialkyl-2-alkenyl sulfones, which upon intramolecular Friedel-Crafts reaction with aluminum chloride gave 1,4-dihydronaphthalenes having a quaternary carbon center. Copyright
Copper-Catalyzed Regio- and Stereoselective 1,6-Conjugate Addition of Aza-Heterocycles to 1-Sulfonyl-1,3-dienes
Park, Subin,Lee, Hanseul,Lee, Yunmi
, p. 572 - 584 (2020)
An efficient and straightforward method for the synthesis of new and versatile sulfonyl-functionalized allylic amines through the selective copper-catalyzed aza-1,6-conjugate addition of heterocycles or arylamines to 1,4-disubstituted-1,3-dienyl sulfones has been developed. This catalytic process is promoted by a combination of an easily prepared and sterically demanding N-heterocyclic carbene-based copper complex and KOt-Bu under mild reaction conditions to provide a broad range of (E)-allylic amines with excellent regio- and stereoselectivities. (Figure presented.).
SYNTHESES WITH SULFONES XLV: STEREOSELECTIVE PREPARATION OF 1- BENZENESULFONYL-1,3-DIENES
Cuvigny, T.,Penhoat, C. Herve du,Julia, M.
, p. 5321 - 5328 (2007/10/02)
The stereoselective preparation of EE 1-benzenesulfonyl-1,3-dienes is described.Michael addition and Diels-Alder cycloaddition of these compounds are reported.
Synthesis of α,β-γ,δ-unsaturated sulfones and sulfoxides via the Horner-Emmons reaction
Jong, B. E. de,Koning, H. de,Huisman, H. O.
, p. 410 - 414 (2007/10/02)
α,β-γ,δ-Unsaturated sulfones and sulfoxides have been prepared via the Horner-Emmons reaction of α,β-unsaturated carbonyl compounds with α-phosphoryl sulfones and sulfoxides.
