803-20-3

Usage

General Description

Benzenamine, 4,4'-(phenylphosphinylidene)bis[N,N-dimethyl- is a chemical compound containing a benzene ring with amine functional groups and a phosphorous atom attached. It is commonly used as a ligand in coordination chemistry, acting as a chelating agent to form stable complexes with metal ions. Benzenamine, 4,4'-(phenylphosphinylidene)bis[N,N-dimethyl- has potential applications in catalysis, organic synthesis, and as a building block in the manufacturing of other chemicals. Its ability to form coordination complexes with metal ions gives it unique properties and makes it useful in various industrial processes. Additionally, it is important to handle Benzenamine, 4,4'-(phenylphosphinylidene)bis[N,N-dimethyl- with care, as it may pose health and safety risks if not managed properly.

Upstream product

• 84127-06-0 bis[4-(N,N-dimethylaminephenyl)]phosphine oxide 
• 66003-76-7 Diphenyliodonium triflate 
• 98-80-6 phenylboronic acid 

Relevant academic research and scientific papers

Nickel-catalyzed C-P cross-coupling of arylboronic acids with P(O)H compounds

A novel and efficient Ni-catalyzed coupling of a wide range of arylboronic acids with H-phosphites, H-phosphinate esters, and H-phosphine oxides has been developed, providing a general and powerful tool for the synthesis of various aryl-phosphorus compounds, especially for valuable triarylphosphine oxides, in good to excellent yield. This protocol is the first Ni-catalyzed C-P bond-forming reaction between arylboronic acids and P(O)H compounds.

Copper-catalyzed P-arylation via direct coupling of diaryliodonium salts with phosphorus nucleophiles at room temperature

A new method for copper-catalyzed P-C bond formation through reaction of phosphorus nucleophiles with diaryliodonium salts at room temperature is described. Most target products are obtained with this method in high yields within a short reaction time of 10 min. It can be easily adapted to large-scale preparations. When unsymmetrical iodonium salts are employed, nucleophilic substitution occurs preferentially on the sterically hindered aromatic ring or the more electron-deficient ring.