84127-06-0

Basic information

• Product Name: bis[4-(N,N-dimethylaminephenyl)]phosphine oxide
• Synonyms: bis[4-(N,N-dimethylaminephenyl)]phosphine oxide
• CAS NO: 84127-06-0
• Molecular Weight: 288.329
• Mol File: 84127-06-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: bis[4-(N,N-dimethylaminephenyl)]phosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: bis[4-(N,N-dimethylaminephenyl)]phosphine oxide(84127-06-0)
• EPA Substance Registry System: bis[4-(N,N-dimethylaminephenyl)]phosphine oxide(84127-06-0)

Safety Data

• Hazardous Substances Data: 84127-06-0(Hazardous Substances Data)

Upstream product

• 121-69-7 N,N-dimethyl-aniline 
• 762-04-9 phosphonic acid diethyl ester 
• 7353-91-5 4-dimethylaminophenylmagnesium bromide 
• 762-04-9 Diethyl phosphonate 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 698-69-1 4-chloro-N,N-dimethylaniline 

Downstream Products

• 35003-61-3 N-{[Bis-(4-dimethylamino-phenyl)-phosphinoyl]-phenyl-methyl}-4-chloro-benzenesulfonamide 
• 84127-04-8 bis(4-methoxyphenyl)phosphine 
• 125518-43-6 tetrakisbisphosphine 
• 81542-31-6 bismethylphosphine oxide 
• 803-20-3 bis(4-(N,N'-dimethylamine)phenyl)phenylphosphine oxide 
• 1769-51-3 bis-(4-dimethylaminophenyl)phosphine 

Relevant articles and documents

Visible-light-driven metal-free aerobic synthesis of highly diastereoselective phosphinoylpyrroloindoles

A visible-light-driven metal-free phosphorus radical mediated construction of 2-phosphinoyl-3H-pyrrolo[1,2,a]indoles is described. This mild tandem phosphinoylation/cyclization protocol utilizes air as a green oxidant and proceeds in a short span of time at room temperature with high functional group tolerance, and excellent chemo- A nd diastereoselectivity.

Preparation of O-Protected Cyanohydrins by Aerobic Oxidation of α-Substituted Malononitriles in the Presence of Diarylphosphine Oxides

A mild, reagent-cyanide-free, and efficient synthesis of O-phosphinoyl-protected cyanohydrins from readily available α-substituted malononitriles was realized using diarylphosphine oxides in the presence of O2. Mechanistic studies indicated that in addition to the initial aerobic oxidation of the malononitrile derivative notable features of this process include the formation of a tetrahedral intermediate and a subsequent intramolecular rearrangement. The phosphinoyl-protecting group can be removed by alcoholysis or by reduction with DIBAL-H.

Synthesis and Characterization of Manganese(I) Carbonyl Complexes of the Type [(OC)4Mn{μ-P(R)Aryl}]2

Metalation of secondary phosphanes HPRR′ [R = R′ = C6H4-4-Me, C6H3-3,5-Me2 (3), C6H4-4-NMe2 (4); R/R′ = Ph/cHex] with Mn2(CO)10 in boiling xylene