80311-85-9Relevant academic research and scientific papers
Efficient solvent free synthesis of tertiary α-aminophosphonates using H2Ti3O7 nanotubes as a reusable solid-acid catalyst
Reddy, Bhoomireddy Rajendra Prasad,Reddy, Peddiahgari Vasu Govardhana,Reddy, Bijivemula N.
, p. 9605 - 9610 (2015)
In this paper, TiO2 fine particles, TiO2-P25, protonated trititanate (H2Ti3O7) nanorods and nanotubes were used as recyclable solid-acid catalysts for the solvent free synthesis of tertiary α-aminopho
Copper-catalyzed α-amination of phosphonates and phosphine oxides: A direct approach to α-amino phosphonic acids and derivatives
McDonald, Stacey L.,Wang, Qiu
supporting information, p. 1867 - 1871 (2014/03/21)
A direct approach to important α-amino phosphonic acids and its derivatives has been developed by using copper-catalyzed electrophilic amination of α-phosphonate zincates with O-acyl hydroxylamines. This amination provides the first example of C=N bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step. The reaction is readily promoted at room temperature with as little as 0.5 mol % of catalyst, and demonstrates high efficiency on a broad substrate scope. A direct approach to important α-amino phosphonic acids and derivatives, by using copper-catalyzed electrophilic amination of α-phosphonate zincates using O-acylhydroxylamines, is described. This amination is the first example of C=N bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step. The reaction proceeds at room temperature with as little as 0.5 mol % of the catalyst. Copyright
UTILISATION EN SYNTHESE DU CATION IMINIUM GENERE IN SITU PAR OXYDATION ELECTROCHIMIQUE D'AMINES TERTIAIRES
Bidan, Gerard,Genies, Martial
, p. 2297 - 2302 (2007/10/02)
The electrochemical oxidation in acetonitrile of aliphatic amines (ACH3) in presence of a non-nucleophilic base (2,4,6-collidine) and of compounds containing weakly-activated hydrogens (RH) such as diethyl phosphonate and diethyl malonate gives the substituted derivatives ACH2R.These compounds result from the addition of the anion R(1-) to the iminium cation ACH2(1+).Such a reaction is obtained with tribenzylamine and N,N-dimethyl-p-toluidine.Moreover (CH3)2NCH2-CH(CO2C2H5)2 is deaminated and gives by successive Michael reactions other substituted malonates which also react with the iminium cation (CH3)2N(1+)=CH2.
