80311-91-7

Upstream product

• 80311-89-3 4-bromo-N-benzylbenzamide 
• 464934-83-6 4-bromo-N-(4-nitrobenzyl)benzamide 
• 586-76-5 4-Bromobenzoic acid 
• 696-60-6 4-aminomethylphenol 

Downstream Products

• 1609658-14-1 4-bromo-N-(3-dipropylaminomethyl-4-hydroxybenzyl)benzamide 
• 1609658-18-5 4-bromo-N-(3-dipropylaminomethyl-4-hydroxybenzyl)-N-methylbenzamide 
• 1609657-26-2 N-(3-dipropylaminomethyl-4-hydroxybenzyl)-4-(2-methylpyridin-4-ylamino)benzamide 

Relevant academic research and scientific papers

NOVEL AMINOMETHYL-PHENOL DERIVATIVES AS ANTIMALARIAL AGENTS

The invention relates to novel aminomethyl-phenol derivatives of formula I wherein R1 to R4, X, A and B are as defined for formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention

AROMATIC HYDROXYLATION OF BENZYLAMIDES BY POTASSIUM SUPEROXIDE

N-benzylamides react with potassium superoxide in benzene in presence of 18-crown-6 ether to give ortho and para hydroxylated products.A mechanism is proposed for this reaction, involving the nucleophilic attack of superoxide anion to amide carbonyl and hydrogen abstraction from benzyle methylene by the substrate-superoxide adduct.