80312-73-8

Upstream product

• 80312-88-5 tert-butyl 2S-(3-hydroxy-2-((4-methylphenyl)sulfonamido)propyl)carbamate 
• 169604-92-6 (S)-3-tert-Butoxycarbonylamino-2-(toluene-4-sulfonylamino)-propionic acid methyl ester 
• 21753-19-5 2-(S)-p-toluenesulfonylamino-β-alanine 
• 16947-86-7 N^α-Tosyl-N^β-(tert-butpxycarbonyl)-L-α,β-diamonopropionic acid 
• 36212-66-5 N²-(toluene-4-sulfonyl)-L-asparagine 

Downstream Products

• 199853-65-1 (S)-3-(3-methylbenzyl)amino-2-(4-toluenesulfonyl)amino-1-propanol 
• 199853-71-9 ethyl (S)-N-methyl-N-{3-[N-(3-methylbenzyl)-N-trifluoroacetyl]amino-2-(4-toluenesulfonyl)amino-1-propyl}aminoacetate 
• 199853-67-3 {[[(S)-3-Hydroxy-2-(toluene-4-sulfonylamino)-propyl]-(3-methyl-benzyl)-carbamoyl]-methyl}-methyl-carbamic acid tert-butyl ester 
• 199853-69-5 (S)-3-[N-(3-methylbenzyl)-N-trifluoroacetyl]amino-2-(4-toluenesulfonyl)amino-1-propanol 
• 199853-70-8 (S)-3-[N-(3-methylbenzyl)-N-trifluoroacetylaminomethyl]-1-(4-toluenesulfonyl)aziridine 
• 199853-76-4 N-[(S)-3-Hydroxy-2-(toluene-4-sulfonylamino)-propyl]-2-methylamino-N-(3-methyl-benzyl)-acetamide 
• 199853-72-0 (S)-N-methyl-N-[3-(3-methylbenzyl)-amino-2-(4-toluenesulfonyl)amino-1-propyl]aminoacetic acid 
• 199853-73-1 4-Methyl-N-[(R)-4-methyl-1-(3-methyl-benzyl)-2-oxo-[1,4]diazepan-6-yl]-benzenesulfonamide 
• 199853-74-2 4-Methyl-N-[(R)-1-methyl-4-(3-methyl-benzyl)-[1,4]diazepan-6-yl]-benzenesulfonamide 

Relevant academic research and scientific papers

Asymmetric synthesis of (R)-6-amino-1-methyl-4-(3-methyl- benzyl)hexahydro-1H-1,4-diazepine from L-asparagine

An efficient asymmetric synthesis of (R)-6-amino-1-methyl-4-(3- methylbenzyl)hexahydro-1H-1,4-diazepine [(R)-2] which serves as the amine part of (R)-1, a potent and selective 5-HT3 receptor antagonist, is described. Formation of the hexahydro-