80322-83-4Relevant academic research and scientific papers
Synthesis of +(1.1.1)>X- Cryptates Assisted by Intramolecular Hydrogen Bonding
Anelli, Pier Lucio,Montanari, Fernando,Quici, Silvio
, p. 3453 - 3457 (2007/10/02)
Condensation of diazacoronand and diethylene glycol bis(methanesulfonate)as well as with its alkylsubstituted derivatives in the presence of 1 molar equiv of BuLi or KH gives the corresponding +(1.1.1)>X- cryptates in 31-43percent yields.Experimental results indicate that in the intermediate monosubstituted diazacoronand, the NH hydrogen plays a templating role, thus favoring the bicyclic ring closure by intramolecular hydrogen bonding.Similar base-promoted condensations of and diazacoronands with triethylene glycol bis(methanesulfonates) afford and cryptates in 20-35percent yields.
