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Usage

Uses

More research is needed to fully understand the potential risks and uses of (2,5-dioxopyrrolidin-1-yl) N-Methyl-N-nitrosocarbaMate. Due to its classification as a nitrosamine and its potential to form carcinogenic metabolites, it is essential to exercise caution when considering its applications in various industries. Further studies should focus on evaluating its safety, efficacy, and potential therapeutic uses before it can be incorporated into any pharmaceutical or industrial applications.

InChI:InChI=1/C6H7N3O5/c1-8(7-13)6(12)14-9-4(10)2-3-5(9)11/h2-3H2,1H3

Upstream product

• 18342-66-0 2,5-dioxopyrrolidin-1-yl methylcarbamate 

Downstream Products

• 83144-39-2 2,2,6,6-tetramethyl-4-(3-methyl-3-nitrosoureido)piperidine-1-oxyl 

Relevant academic research and scientific papers

Synthesis and in vitro antitumor activity of novel 2-alkyl-5- methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazol-2-ium and 2-alkylellipticin-2-ium chloride derivatives

Twenty-one types of novel ellipticine derivatives and pyridocarbazoles (5-methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazoles) with a nitrosourea moiety, linked by an oxydiethylene unit at the 2 position, were synthesized, and their cytotoxicity against HeLa S-3 cells was evaluated. Some of these new compounds exhibited potent antitumor activity by comparison with that of ellipticine.

Activated N-Nitrosocarbamates for Regioselective Synthesis of N-Nitrosoureas

A practical and convenient method for synthesizing antitumor compounds, N-alkyl-N-nitrosoureas, regioselectively nitrosated on the nitrogen atom bearing the alkyl group is proposed.N-Alkyl-N-nitrosocarbamates are interesting intermediates in these syntheses and yield, by reaction with amino compounds, the regioselectively nitrosated N-alkyl-N-nitrosoureas.As an interesting example, N,N'-biscystamine, a new attractive oncostatic derivative, has been prepared.The cytotoxic activity of these various compounds were tested on L1210 leukemia.