83144-39-2

Upstream product

• 36768-62-4 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE 
• 4168-79-0 4-hydroxyimino-2,2,6,6-tetramethylpiperidine 
• 101397-68-6 1-methyl-3-(2'.2'.6'.6'-tetramethylpiperidin-4'-yl)-urea 
• 83144-38-1 1-methyl-3-(2'.2'.6'.6'-tetramethyl-piperidin-4'-yl-1-oxyl)-urea 
• 14691-88-4 4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl 
• 80354-48-9 N-methyl-N-nitrosocarbamic acid N'-hydroxysuccinimide ester 

Relevant academic research and scientific papers

Synthesis of nitroxide derivatives of alkylnitrosourea

Nitroxide derivatives of alkylnitrosoureas were prepared by the reaction of amino nitroxide radicals with activated N-alkyl-N-nitrosocarbamates or by the selective reduction of oxoammonium derivatives of alkylnitrosoureas.

Potential Anticancer Agents. XXVI. Spin Labelled Nitrosoureas

In order to obtain more information about the in vivo mechanism of action of nitrosoureas, the synthesis of spin labelled nitrosoureas derived from 1-oxyl-2.2.6.6-tetramethyl-4-aminopiperidine was undertaken.The synthesis of four spin labelled ureas 4a-4d was reported as well as two spin labelled nitrosoureas: 1-methyl-3-(2'.2'.6'.6'-tetramethyl-piperidin-4'-yl-1'-oxyl)-1-nitrosourea (9a) and 1-(2'-chloroethyl)-3-(2".2".6".6"-tetramethyl-piperidin-4"-yl-1"-oxyl)-1-nitrosourea (9b).Their e.s.r. spectra were recorded.None of these compounds proved to be active against L1210.