80360-15-2 Usage
Molecular Weight
315.36 g/mol The molecular weight is the mass of one mole of the compound, calculated by adding the atomic weights of all the atoms in the molecular formula.
Appearance
White crystalline solid The appearance describes the physical form of the compound, which is a white crystalline solid.
Solubility
Slightly soluble in water, soluble in organic solvents such as ethanol, dichloromethane, and acetonitrile The solubility describes the compound's ability to dissolve in different solvents, with low solubility in water and high solubility in organic solvents.
Melting Point
105-107°C The melting point is the temperature at which the compound changes from a solid to a liquid state.
Functional Groups
Ester, phenylsulfonyl, indole The functional groups are specific chemical structures within the compound that are responsible for its chemical reactivity and properties.
Synthesis
The compound can be synthesized through the reaction of indole-3-carboxylic acid with ethyl chlorosulfone The synthesis describes the process of creating the compound from other chemicals.
Uses
The compound is used as a precursor for the synthesis of pharmaceutical and agrochemical compounds, and as a protective group in organic synthesis The uses describe the practical applications of the compound in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 80360-15-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,6 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 80360-15:
(7*8)+(6*0)+(5*3)+(4*6)+(3*0)+(2*1)+(1*5)=102
102 % 10 = 2
So 80360-15-2 is a valid CAS Registry Number.
80360-15-2Relevant academic research and scientific papers
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: Synthesis and SAR studies
Silvestri, Romano,De Martino, Gabriella,La Regina, Giuseppe,Artico, Marino,Massa, Silvio,Vargiu, Laura,Mura, Massimo,Loi, Anna Giulia,Marceddu, Tiziana,La Colla, Paolo
, p. 2482 - 2493 (2007/10/03)
The potent anti-HIV-1 activities of L-737,126 (2) and PAS sulfones prompted us to design and test against HIV-1 in acutely infected MT-4 cells a number of novel 1- and 3-benzenesulfonylindoles. Indoles belonging to the 1-benzenesulfonyl series were found
Generation and Reactions of 3-Lithio-1-(phenylsulfonyl)indole
Saulnier, Mark G.,Gribble, Gordon W.
, p. 757 - 761 (2007/10/02)
Treatment of 1-(phenylsulfonyl)-3-iodoindole (6) with 2 equiv of tert-butyllithium (-100 deg C THF) generates essentially quantitatively 3-lithio-1-(phenylsulfonyl)indole (1).Quenching 1 with various electrophiles gives 3-substituted indoles in good yield
