80366-17-2

Upstream product

• 80366-16-1 diphenylmethyl 7-(2-thienylacetamido)-2-methyl-3-formyloxymethylceph-2-em-4-carboxylate 
• 70056-19-8 diphenylmethyl 7-(2-thienylacetamido)-2-methylene-3-acetoxymethylceph-3-em-4-carboxylate 

Downstream Products

• 87263-06-7 (6R,7R)-3-Chloromethyl-4-methyl-8-oxo-7-(2-thiophen-2-yl-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2-carboxylic acid benzhydryl ester 
• 80366-50-3 diphenylmethyl 7-(2-thienylacetamido)-2-methyl-3-formylceph-2-em-4-carboxylate 
• 80366-56-9 (4R,6R,7R)-4-Methyl-3-[(2-morpholin-4-yl-ethoxyimino)-methyl]-5,8-dioxo-7-(2-thiophen-2-yl-acetylamino)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 80377-40-8 4-(1,1-diphenylmethylcarbonyl)-7-(2-thienylacetamido)-2α-methyl-3-(1-methyl-1H-tetrazol-5-yl)thiomethylceph-3-em 1-oxide 
• 80366-19-4 diphenylmethyl 7-(2-thienylacetamido)-2α-methyl-3-(1-methyl-1H-tetrazol-5-yl)thiomethylceph-3-em-4-carboxylate 
• 80366-18-3 diphenylmethyl 7-(2-thienylacetamido)-2-methyl-3-(1-methyl-1H-tetrazol-5-yl)thiomethylceph-2-em-4-carboxylate 
• 80366-54-7 diphenyl 7-(2-thienylacetamido)-2α-methyl-3-methoxyiminomethylceph-3-em-4-carboxylate 
• 80366-53-6 4-(1,1-diphenylmethoxycarbonyl)-7-(2-thienylacetamido)-2α-methyl-3-methoxyiminomethylceph-3-em 1-oxide 
• 80366-51-4 4-(1,1-diphenylmethoxycarbonyl)-7-(2-thienylacetamido)-2α-methyl-3-formylceph-3-em 1-oxide 
• 80366-27-4 diphenylmethyl 7-amino-2α-methyl-3-(1-methyl-1H-tetrazol-5-yl)thiomethylceph-3-em-4-carboxylate 

Relevant academic research and scientific papers

Synthesis of 2α-methyl- and 2β-methyl-3-(substituted methyl)cephalosporins, and 2,3-diexomethylenecepham

The stereoselective synthesis of 2α-methyl- and 2β-methyl-3-(substituted methyl)- cephalosporins via 2-methyl-3-formyloxymethylceph-2-em (5) and 2-methyl-3-acetoxymethylceph-2-em (16) from 2-methylene-3-acetoxymethylcephalosporin (1) is described. Reducti