803685-70-3Relevant academic research and scientific papers
A novel oxazine ring closure reaction affording (Z)-((E)-2-styrylbenzo[b]furo[3,2-d][1,3]oxazin-4-ylideno)acetaldehydes and their anti-osteoclastic bone resorption activity
Ando, Yuko,Ando, Kumiko,Yamaguchi, Mami,Kunitomo, Jun-ichi,Koida, Masao,Fukuyama, Ryo,Nakamuta, Hiromichi,Yamashita, Masayuki,Ohta, Shunsaku,Ohishi, Yoshitaka
, p. 5849 - 5854 (2006)
A novel oxazine ring formation method was established using the reaction of 2-acetyl-(E)-3-styrylcarbonylaminobenzo[b]furans (4) with Vilsmeier-Haack-Arnold reagent to afford (E and Z)-((E)-2-styrylbenzo[b]furo[3,2-d][1,3]oxazin-4-ylideno)acetaldehydes (5
Preparation of novel (Z)-4-ylidenebenzo[b]furo[3,2-d][1,3]oxazines and their biological activity
Tabuchi, Yukako,Ando, Yuko,Kanemura, Hidemi,Kawasaki, Ikuo,Ohishi, Takahiro,Koida, Masao,Fukuyama, Ryo,Nakamuta, Hiromichi,Ohta, Shunsaku,Nishide, Kiyoharu,Ohishi, Yoshitaka
experimental part, p. 3959 - 3967 (2009/10/10)
A reaction of 2-acetyl-3-acylaminobenzo[b]furans (9d-o) with Vilsmeier (VM) reagent afforded a mixture of (E)- and (Z)-{(E)-2-aralkenylbenzo[b]furo[3,2-d][1,3]oxazin-4-ylidene}acetaldehydes (5) with a characteristic exo-formylmethylene group on the oxazin
BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME
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Page/Page column 57, (2008/06/13)
The present invention relates to a benzofuran compound of the formula (I) wherein each symbol is as defined in the description, a pharmaceutically acceptable salt thereof and the like. The compound of the present invention has superior leukotriene inhibitory action, BLT2 competitive inhibitory action, BLT2 blocking action, action for the prophylaxis or treatment of allergy, action for the prophylaxis or treatment of asthma and action for the prophylaxis or treatment of inflammation, and is useful as an agent for the prophylaxis or treatment of diseases such as allergic disease, asthma, inflammation and the like, and other diseases.
