80375-66-2

Upstream product

• 28028-68-4 Crassin acetate 
• 80375-70-8 (9E,13E)-(3S,3aS,5S,6R,15aS)-5,6-Dihydroxy-6,10,14-trimethyl-3-phenylsulfanylmethyl-3a,4,5,6,7,8,11,12,15,15a-decahydro-3H-1-oxa-cyclopentacyclotetradecen-2-one 
• 80375-68-4 isocrassin alcohol 
• 28068-69-1 (4E,8E)-2,10-dihydroxy-4,8,12-trimethyl-16-methylidene-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-15-one 
• 108-98-5 thiophenol 

Downstream Products

• 80375-70-8 (9E,13E)-(3S,3aS,5S,6R,15aS)-5,6-Dihydroxy-6,10,14-trimethyl-3-phenylsulfanylmethyl-3a,4,5,6,7,8,11,12,15,15a-decahydro-3H-1-oxa-cyclopentacyclotetradecen-2-one 
• 28068-69-1 (4E,8E)-2,10-dihydroxy-4,8,12-trimethyl-16-methylidene-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-15-one 
• 80375-68-4 isocrassin alcohol 
• 91465-20-2 (4E,8E)-(1S,2S,12R,13S,16R)-2,12-Dihydroxy-4,8,12-trimethyl-16-phenylsulfanylmethyl-14-oxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-one 

Relevant academic research and scientific papers

Interconversion of Cembranolide &δ- and &γ-Lactones: Synthesis of the C-1 Epimer of Isolobophytolide

The δ-lactone cembranolide diterpene crassin alcohol (2) has been converted to an isomeric γ-lactone isocrassin alcohol (6) by a sequence involving kinetically controlled addition of benzenethiol to the conjugated lactone double bond followed by base-prom