80375-68-4

Usage

Uses

Used in Pharmaceutical Industry:
(9E)-5,6-dihydroxy-6,10,14-trimethyl-3-methylidene-3a,4,5,6,7,8,11,12,15,15a-decahydrocyclotetradeca[b]furan-2(3H)-one is used as a potential pharmaceutical compound for [application reason] due to its unique structure and properties. Further research is required to determine its specific uses and potential benefits in this industry.
Used in Chemical Industry:
In the chemical industry, (9E)-5,6-dihydroxy-6,10,14-trimethyl-3-methylidene-3a,4,5,6,7,8,11,12,15,15a-decahydrocyclotetradeca[b]furan-2(3H)-one is used as a [application type] for [application reason]. Its complex structure and functional groups may offer novel opportunities for chemical synthesis and material development.

Upstream product

• 80375-66-2 (4E,8E)-(1S,2S,12R,13S,16S)-2,12-Dihydroxy-4,8,12-trimethyl-16-phenylsulfanylmethyl-14-oxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-one 
• 28028-68-4 Crassin acetate 
• 28068-69-1 (4E,8E)-2,10-dihydroxy-4,8,12-trimethyl-16-methylidene-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-15-one 
• 80375-70-8 (9E,13E)-(3S,3aS,5S,6R,15aS)-5,6-Dihydroxy-6,10,14-trimethyl-3-phenylsulfanylmethyl-3a,4,5,6,7,8,11,12,15,15a-decahydro-3H-1-oxa-cyclopentacyclotetradecen-2-one 

Downstream Products

• 28068-69-1 (4E,8E)-2,10-dihydroxy-4,8,12-trimethyl-16-methylidene-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-15-one 
• 91465-20-2 (4E,8E)-(1S,2S,12R,13S,16R)-2,12-Dihydroxy-4,8,12-trimethyl-16-phenylsulfanylmethyl-14-oxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-one 
• 80375-66-2 (4E,8E)-(1S,2S,12R,13S,16S)-2,12-Dihydroxy-4,8,12-trimethyl-16-phenylsulfanylmethyl-14-oxa-bicyclo[11.3.1]heptadeca-4,8-dien-15-one 

Relevant academic research and scientific papers

Synthesis of analogues of Eunicea γ-cembranolides containing cyclic ethers via saponification

A method for the synthesis of derivatives of the lead structures euniolide (1), 12,13-bisepieupalmerin (2), and eupalmerin acetate (3) containing tetrahydrofuran and tetrahydropyran ring systems was developed on the basis of alkali-induced intramolecular oxacyclizations. Representatives of the new analogues were submitted to the in vitro antitumor cell-line-screening program of the National Cancer Institute (NCI). While it was shown that a variety of structural modifications are possible, these transformations led typically to nontoxic synthetic cembranoids.

Interconversion of Cembranolide &δ- and &γ-Lactones: Synthesis of the C-1 Epimer of Isolobophytolide

The δ-lactone cembranolide diterpene crassin alcohol (2) has been converted to an isomeric γ-lactone isocrassin alcohol (6) by a sequence involving kinetically controlled addition of benzenethiol to the conjugated lactone double bond followed by base-prom