80391-28-2

Upstream product

• 4457-32-3 4-nitrobenzyl chloroformate 
• 77526-92-2 (1'RS,3SR,4RS)-4-allyl-1-(dimethyl-t-butylsilyl)-3-(1-hydroxyethyl)-azetidin-2-one 
• 107668-31-5 (1'RS,3SR,4RS)-4-allyl-1-(dimethyl-t-butylsilyl)-3-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-azetidin-2-one 
• 68485-52-9 4-allylazetidin-2-one 
• 7393-43-3 tetraallyl tin 
• 72888-48-3 Acetic acid (R)-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-2-yl ester 
• 96543-03-2 Benzoic acid (R)-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-2-yl ester 

Downstream Products

• 107685-91-6 p-nitrobenzyl (1'RS,3SR,4RS)-<4-allyl-3-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-2-oxoazetidin-1-yl>(triphenylphosphoranylidene)acetate 
• 107685-93-8 p-nitrobenzyl (1'RS,3aRS,4aRS,5SR,7aRS)-3a,4,4a,5,6,7a-hexahydro-5-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-6-oxo-3H-azeto<1',2':1,5>pyrrolo<2,3-c>pyrazole-7a-carboxylate 
• 107685-89-2 {(2R,3S)-2-Allyl-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-chloro-acetic acid 4-nitro-benzyl ester 
• 107668-32-6 p-nitrobenzyl (1'RS,2SR,4RS,6RS,7SR)-7-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-8-oxo-1-azatricyclo<4.2.0.0^2,4>octane-2-carboxylate 
• 107685-92-7 p-nitrobenzyl 3-methyl-6-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 87568-67-0 p-nitrobenzyl (1'RS,5RS,6SR)-6-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 107685-88-1 p-nitrobenzyl (1'RS,3SR,4RS)-<4-allyl-3-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-2-oxoazetidin-1-yl>hydroxyacetate 

Relevant academic research and scientific papers

Olivanic Acid Analogues. Part 4. Cycloaddition Reactions of p-Nitrobenzyl 7-Oxo-1-azabicyclohept-2-ene-2-carboxylate, and Synthesis of the 8-Oxo-1-azatricyclo2,4>octane-2-carboxylate System

p-Nitrobenzyl 7-oxo-1-azabicyclohept-2-ene-2-carboxylate (1) participated in Diels-Alder and 1,3-dipolar cycloaddition reactions, yielding a range of novel polycyclic azetidinone structures.The two 8-oxo-1-azatricyclo2,4>octane-2

7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, their use and preparation

7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives of formula (I): STR1 (in which:) R1 represents a hydrogen atom or an optionally substituted alkyl group; X represents an oxy group, a thio group, a sulphinyl group or a sulphonyl group; A represents a bivalent for trivalent saturated aliphatic hydrocarbon group; p is 1 (when A is bivalent) or 2 (when A is trivalent); R2 represents an azido, nitro or cyano group or one of the groups of formula STR2 m and n are the same or different and each is 0 or 1; R represents an amidino group or a group of formula R4, --N(R4)2 or --YR4, B represents a group of formula STR3 D represents a group of formula STR4 (provided that, where m and n are both 1, the groups represented by B and D must be different); R4 represents a hydrogen atom or an alkyl group and, where there are 2 or more groups represented by R4, they may be the same or different, and Y represents an oxygen atom or a sulphur atom; and R3 represents a carboxy group or a protected carboxy group) and pharmaceutically acceptable salts thereof are valuable antibiotics and may be prepared by a process which includes heating a corresponding phosphorus-ylide compound.