80420-93-5Relevant academic research and scientific papers
Cation radical induced cycloaddition reaction between aryl imines and ethyl diazoacetate
Huo, Congde,Sun, Chougu,Hu, Dongcheng,Jia, Xiaodong,Xu, Xiaolan,Liu, Zhongli
scheme or table, p. 7008 - 7010 (2012/02/05)
The reaction of ethyl diazoacetate with aryl imines can be initiated by persistent cation radical salt tris(4-bromophenyl)aminium hexachloroantimonate, giving exclusively cis-aziridine carboxylates.
β-Enamino esters in heterocyclic synthesis: Synthesis of pyrazolone and pyridinone derivatives
Salaheldin, Abdellatif Mohamed,Al-Sheikh, Mariam Abdullah
experimental part, p. 4359 - 4368 (2010/10/01)
An efficient and convenient synthesis of pyrrolidinones and pyridinones utilizing enamino esters as starting material has been described. The structures of the compounds obtained were confirmed by spectral and elemental analyses.
Catalytic preparation of aziridines with an iron lewis acid
Mayer, Michael F.,Mahmun Hossain
, p. 6839 - 6844 (2007/10/03)
The iron Lewis acid, [(;75-C5H5)Fe(CO)2(THF)]+[BF4]-) was found to be an effective catalyst for the preparation of aziridines. This new method provides a facile, one-step route to predominantly cisaziridines, with yields up to 95%, from compounds with a diazo functionality and a variety of substituted AT-benzylidene imines with N-aryl or AT-alkyl groups. The reaction mechanism is believed to proceed through an electrophilic iminium ion intermediate. To support this idea, the iron Lewis acid-imine complex [(?75-C5H5)Fe(CO)2(PhCH=NPh)]+[BF.j]- was prepared, characterized, and reacted with different diazo compounds to provide the resultant czs-aziridines. Alternatively, it may be possible that the aziridines were derived from an electrophilic carbenoid intermediate, as is often proposed. Thus, the iron carbene [(2-CsIWFeCCOMCHPhOl+LSOaCFg]- was prepared and treated with AT-benzylideneaniline; however, the resultant aziridine was not formed.
β,β-Diacyl-enamine und -enole, 9. Zur Darstellung von Aminomethylenderivaten offenkettiger CH2-acider Verbindungen
Wolfbeis, Otto S.
, p. 3471 - 3484 (2007/10/02)
The reaction of a combination of primary or secondary aromatic or aliphatic amines with orthocarboxylic esters upon a variety of open-chain CH2-acidic molecules gives N-substituted aminoalkylidene derivatives.The method is highly recommended for methylene
