80420-96-8

Upstream product

• 27673-58-1 N,N-Dimethyl-N'-(α-cyano-β-dimethylaminoacrylyl)formamidine 
• 62-53-3 aniline 
• 107-91-5 cyanoacetic acid amide 
• 149-73-5 trimethyl orthoformate 
• 1783-25-1 N₁,N₁-dimethyl-N₂-phenylformamidine 
• 91255-20-8 N,N-Dimethyl-N'-(α-cyano-β-N'-anilinoacrylyl)formamidine 
• 91255-26-4 1-phenyl-5-cyano-1,4-dihydropyrimidin-4-one 

Downstream Products

• 1202-48-8 N-(2,2-dicyanovinyl)-aniline 
• 145162-29-4 3-amino-4-carbamoyl-1-phenyl-pyrrol-2-carbonsaeureethylester 
• 91255-20-8 N,N-Dimethyl-N'-(α-cyano-β-N'-anilinoacrylyl)formamidine 
• 88796-36-5 4-amino-1-phenyl-pyrrol-3-carboxamid 

Relevant academic research and scientific papers

ACETALS OF LACTAMS AND ACID AMIDES. 41. ENAMINO AMIDES IN THE SYNTHESIS OF PYRIMIDINE DERIVATIVES

The reaction of α-cyano-β-dimethylaminomethyleneacrylamide with arylamines was used to synthesize α-cyano-β-arylaminoacrylamides, which react readily with dimethylformamide diethylacetal to give the corresponding N-dimethylaminomethylene derivatives.The latter undergo cyclization to 1-aryl-5-cyano-4-pyrimidinones when they are heated in dimethylformamide or acetic anhydride and to pyrimidoquinolone derivatives when they are heated in glacial acetic acid.

β,β-Diacyl-enamine und -enole, 9. Zur Darstellung von Aminomethylenderivaten offenkettiger CH2-acider Verbindungen

The reaction of a combination of primary or secondary aromatic or aliphatic amines with orthocarboxylic esters upon a variety of open-chain CH2-acidic molecules gives N-substituted aminoalkylidene derivatives.The method is highly recommended for methylene