1783-25-1

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 25, p. 2245, 1960 DOI: 10.1021/jo01082a619

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 2040-76-8 phenylcarbamic acid chloride 
• 60-29-7 diethyl ether 
• 62-53-3 aniline 
• 67250-04-8 5,5-dimethyl-1-phenyl-1,2,5-triazapentadiene 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 587-65-5 N-chloroacetyl-aniline 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 
• 103-70-8 Formanilid 
• 5909-67-1 tetramethyldiamidothiophosphoric acid 
• 917-58-8 potassium ethoxide 
• 101-42-8 fenuron 
• 1256844-19-5 C₉H₁₂N₂O 

Downstream Products

• 1214-75-1 2,4-Dinitro-ω-dimethylamino-styrol 
• 5336-72-1 dimethyl(diphenylmethyl)amine 
• 2305-54-6 2-(Anilinomethylen)-2-cyanessigsaeure-ethylester 
• 5378-52-9 phenyl-1H-tetrazole 
• 637-51-4 isothiocyanatobenzene 
• 78158-97-1 C₇H₇NSe 
• 68-12-2 N,N-dimethyl-formamide 
• 62-53-3 aniline 
• 197079-08-6 ethyl 1-phenyl-1H-imidazole-4-carboxylate 
• 123366-37-0 [1-(1-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)-meth-(E)-ylidene]-phenyl-amine 
• 1202-48-8 N-(2,2-dicyanovinyl)-aniline 
• 91255-20-8 N,N-Dimethyl-N'-(α-cyano-β-N'-anilinoacrylyl)formamidine 
• 100-61-8 N-methylaniline 
• 80420-96-8 α-Cyano-β-anilinoacrylamide 

Relevant academic research and scientific papers

Anomalous Products from 1,2,5-Triaza- and 1,5-Diaza-pentadiene Thermolyses: Formation of Amidines and Pyrroles, respectively

Gas-phase thermolysis of the dimethylaminoazoalkene (1) gives the formamidine (2) by loss of HCN: in contrast, the related 1,5-diazapentadiene (4) under more forcing conditions gives aniline (30percent) and N-methylpyrrole (43percent).

Acylation of tertiary amides. Formation of 1-acyloxyiminium salts and 1-acyloxyenamines

Tertiary carboxamides are acylated at the oxygen atom by benzoyl or acetyl chloride in the presence of silver trifluoromethanesulphonate; if the resulting 1-acyloxyiminium salts contain hydrogen atoms at positions 2 or 4 they can be deprotonated to yield unstable 1-acyloxy-enamines or -dienamines, which have been trapped by reaction with 4-phenyl-1,2,4-triazoline-3,5-dione.

3-Aminothieno[2,3-b]pyridine-2-carboxylate: Effective precursor for microwave-assisted three components synthesis of new pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one hybrids

In this study, ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate was taken as a versatile precursor for the one-pot three-component synthesis of related fused pyrimidine hybrids. The tandem protocol involved the reaction of 3-aminothieno[2,3-b]pyridine, di

Novel synthesis of 1-substituted-4-imidazolecarboxylates via solvent-free cycloaddition reaction between formamidines and isocyanides

A simple and efficient protocol for cyclization between formamidines and ethyl isocyanoacetate has been described in the absence of metal catalyst and solvent. A series of 1-substituted-4-imidazolecarboxylates were synthesized in moderate to good yields with DABCO as base additive.

Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMF: Via copper-catalyzed C(sp3)-H amidination

A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp3)-H amidination. Various methyl ketones react readily with aromatic amines a

C–N cross-coupling on supported copper catalysts: The effect of the support, oxidation state, base and solvent

A series of supported copper catalysts at two different loadings (1 and 2?wt%) have been prepared by deposition precipitation on various supports including TiO2, ZnO, Al2O3 and active carbon and submitted or not to reductive treatments to favor the increase in population of Cu(I). The samples have been characterized by textural measurements, electron microscopy and spectroscopic techniques including EPR and XPS, concluding the presence of dispersed copper oxides on the support with small particle size and contrasting prevalence of Cu(II) or Cu(I). The catalytic activity of all these catalysts for the C–N coupling of aniline and bromobenzene has been evaluated. A strong influence of the support, copper oxidation state, solvent, nature of the base was observed, the optimal conditions being the use of ZnO or TiO2 as supports and toluene/dioxane as solvent and EtOK as base. t-C5H11OK as base in either THF or toluene give rise to the formation of t-C5H11 phenyl ether in some extent. The catalyst undergoes deactivation during the reaction, but about 88% of the activity of the fresh sample could be regained by dioxane washings before reuse. XPS indicates that the most likely origin of catalyst deactivation is adsorption on the copper catalyst surface of KBr and inorganic salts formed as byproducts during the reaction.

Chromatographic and chromato-mass spectral characterization of amino acids derivatives formed via the interaction with dimethyl acetal of dimethylformamide

A series of amino acids have been converted into the derivatives via interaction with dimethylformamide dimethyl acetal for gas chromatography identification. The derivatives have been for the first time characterized with mass spectra and retention indices corresponding to the standard nonpolar polydimethylsiloxane stationary phases. Basic features of mass spectroscopic fragmentation of the derivatives have been stated; the rules for interpretation of their gas chromatography retention indices have been figured out, including the additive scheme elements.

Method For Preparing Formamidines

A method for preparing formamidines of formula (I) in a single step by reducing ureas of formula (II) using silanes of formula (III), according to reaction (II)+(III)+(I) is provided. The present invention also provides a method for preparing insecticides

Pushing back the limits of hydrosilylation: Unprecedented catalytic reduction of organic ureas to formamidines

Pushing back the limits: A novel catalytic transformation has been designed to prepare formamidine derivatives by reduction of substituted ureas with hydrosilanes. Simple iron catalysts based on commercially available iron salts and phosphine ligands prov

Synthetic potentiality of α-amino nitrones as oxidizing reagent in the conversion of alkyl halides to aldehydes

α-Amino nitrones have been used successfully as an oxidizing reagent for the synthesis of aldehydes from various alkyl halides with an excellent yield. In addition, hydrolysis of the side product (imines) furnishes starting material amides which are recyclable along with corresponding amines.