80442-87-1

Upstream product

• 103-80-0 phenylacetyl chloride 
• 657-27-2 L-Lysine hydrochloride 
• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 
• 18836-42-5 N^ε-phenylacetyl-L-lysine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 80442-90-6 L-prolyl-N^ε-phenylacetyl-L-lysyl-glycine hydrobromide 
• 80442-89-3 N^α-benzyloxycarbonyl-L-prolyl-N^ε-phenylacetyl-L-lysyl-glycine amide 
• 80442-88-2 N^ε-phenylacetyl-L-lysyl-glycine amide hydrobromide 
• 80442-94-0 N^α-benzyloxycarbonyl-N^ε-phenylacetyl-L-lysyl-glycine amide 

Relevant academic research and scientific papers

Subtype selective substrates for histone deacetylases

To probe the steric requirements for deacylation, we synthesized lysine-derived small molecule substrates and examined structure-reactivity relationships with various histone deacetylases. Rat liver, human HeLa, and human recombinant class I and II histon

USE OF PHENYLACETYL GROUP FOR PROTECTION OF THE LYSINE N&ε-AMINO GROUP IN SYNTHESIS OF PEPTIDES

Nε-Phenylacetyllysine was used in the synthesis of deamino-lysine-vasopressin.The phenylacetyl protecting group is stable under conditions of peptide synthesis and can be removed by action of penicillin amidohydrolase (E.C.3.5.1.11) without dam