804556-39-6Relevant articles and documents
Enzymatic acylation reactions on ω-hydroxycyanohydrins
Gonzalo, Gonzalo De,Lavandera, Iván,Brieva, Rosario,Gotor, Vicente
, p. 10525 - 10532 (2007/10/03)
The enzymatic acylation of certain ω-hydroxycyanohydrins protected at the primary alcohol has been studied. The best enantioselectivities are obtained with Pseudomonas cepacia lipase (PSL-C) and Candida antarctica lipase A (CAL-A), for the ω-O-tritylated cyanohydrins. The effect of the protecting group in the enzymatic reactions has been studied using molecular modeling. Graphical abstract.