80459-48-9

Basic information

• Product Name: 4-[[(4-methylphenyl)sulfonyl]oxy]benzaldehyde
• Synonyms: 4-[[(4-methylphenyl)sulfonyl]oxy]benzaldehyde
• CAS NO: 80459-48-9
• Molecular Formula: C₁₄H₁₂O₄S
• Molecular Weight: 276.31
• Mol File: 80459-48-9.mol
• Article Data: 32

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[[(4-methylphenyl)sulfonyl]oxy]benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[[(4-methylphenyl)sulfonyl]oxy]benzaldehyde(80459-48-9)
• EPA Substance Registry System: 4-[[(4-methylphenyl)sulfonyl]oxy]benzaldehyde(80459-48-9)

Safety Data

• Hazardous Substances Data: 80459-48-9(Hazardous Substances Data)

Upstream product

• 35616-03-6 4-hydroxyphenyl 4-methyl-1-benzenesulfonate 
• 15226-74-1 dicobalt octacarbonyl 
• 6324-15-8 toluene-4-sulfonic acid 4-bromo-phenyl ester 
• 201230-82-2 carbon monoxide 
• 82102-37-2 9-methyl-9H-fluorene-9-carbonyl chloride 
• 24962-55-8 4-hydroxybenzaldehyde 4-methylbenzenesulfonate ester 
• 590-29-4 potassium formate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 882970-92-5 1-(4-hydroxybenzyl)isoquinoline N-oxide 
• 178469-37-9 4-(bromomethyl)phenyl 4-methylbenzenesulfonate 
• 133740-27-9 (2,4-dimethoxyphenyl)((2S,3S,3aS,4S,9bR)-7-methoxy-2,4-bis(4-methoxyphenyl)-2,3,3a,9b-tetrahydro-4H-furo[3,2-c]chromen-3-yl)methanone 
• 133740-28-0 (2,4-dihydroxyphenyl)((2S,3S,3aS,4S,9bR)-7-hydroxy-2,4-bis(4-hydroxyphenyl)-2,3,3a,9b-tetrahydro-4H-furo[3,2-c]chromen-3-yl)methanone 
• 1109280-50-3 4-ethynylphenyl 4-methylbenzene-1-sulfonate 
• 3218-36-8 4-Phenylbenzaldehyde 
• 1581275-73-1 4-((ethylamino)methyl)phenyl 4-methylbenzenesulfonate 
• 1581275-72-0 4-((N-ethyl-4-phenylquinazoline-2-carboxamido)methyl)-phenyl 4-methylbenzenesulfonate 
• 1581275-47-9 N-ethyl-N-(4-hydroxybenzyl)-4-phenylquinazoline-2-carboxamide 

Relevant articles and documents

Total synthesis of phorbazole B

Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the trichlorinated phorbazole B using late stage electrophilic chlorination was developed. The synthesis relied on the use of an oxazole precursor, which was protected with an iodine in the reactive 4-position, followed by complete chlorination of all pyrrole positions. Attempts to prepare phorbazole A and C, which contain a 3,4-dichlorinated pyrrole, were unsuccessful as the desired chlorination pattern on the pyrrole could not be obtained. The identities of the dichlorinated intermediates and products were determined using NMR techniques including NOESY/ROESY, 1,1-ADEQUATE and high-resolution CLIP-HSQMBC.

Synthesis and anticancer activity of novel hydrazone linkage-based aryl sulfonate derivatives as apoptosis inducers

In the present study, the various 28 hybrid molecules containing hydrazone and sulfonate moieties were synthesized and characterized by FTIR, 1H-NMR, 13C-NMR spectroscopy and LC-MS spectrometry, besides elemental analysis. The compou

NaI-mediated oxidative amidation of benzyl alcohols/aromatic aldehydes to benzamides via electrochemical reaction

In this research, we have developed a mild electrochemical process for oxidative amidation of benzyl alcohols/aromatic aldehydes with cyclic amines into the corresponding benzamides. This electroorganic synthetic method proceeds using NaI as a redox mediator under ambient temperature in undivided cell, providing more than 25 examples of amide products in moderate to good yields. The benefits of this reaction include one-pot synthesis, open air condition, proceed in aqueous media and no requirement of external conducting salt, base and oxidant.