24962-55-8

Usage

Uses

Used in Organic Synthesis:
4-IODOPHENYL 4-METHYLPHENYLSULFONATE is used as a reagent for the preparation of aromatic compounds, playing a crucial role in the synthesis process.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4-IODOPHENYL 4-METHYLPHENYLSULFONATE is used as a reactant for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Production:
4-IODOPHENYL 4-METHYLPHENYLSULFONATE is also utilized in the production of agrochemicals, serving as a key component in the synthesis of compounds used in agriculture.
Used in Fine Chemicals Synthesis:
4-IODOPHENYL 4-METHYLPHENYLSULFONATE is used as a reactant in the synthesis of fine chemicals, which are important for a variety of applications, including fragrances, dyes, and other specialty chemicals.
Used in Material Science:
4-IODOPHENYL 4-METHYLPHENYLSULFONATE has potential applications in the field of material science, where it can be employed in the development of new materials and chemical processes, showcasing its versatility and value in research and industrial settings.

InChI:InChI=1/C13H11IO3S/c1-10-2-8-13(9-3-10)18(15,16)17-12-6-4-11(14)5-7-12/h2-9H,1H3

Upstream product

• 540-38-5 p-Iodophenol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 455-16-3 p-toluenesulfonyl fluoride 
• 98-59-9 p-toluenesulfonyl chloride 
• 1073-72-9 4-hydroxythioanisole 

Downstream Products

• 1598432-06-4 4-(2,2,2-trifluoroethyl)phenyl 4-methylbenzenesulfonate 
• 101110-81-0 (E)-3-(4-(tosyloxy)phenyl)prop-2-enoic acid 
• 51804-15-0 4-carboxyphenyl 4-methylbenzenesulfonate 
• 1265145-22-9 6-(4-toluenesulfonyloxy)-1,2,3,4-tetrahydrocarbazole 
• 1265145-01-4 di-tert-butyl 1-(4-(tosyloxy)phenyl)hydrazine-1,2-dicarboxylate 
• 1186721-89-0 4-(5-(1-methyl-6-oxo-1,4,5,6-tetrahydropyridin-3-yl)pent-1-ynyl)phenyl 4-methylbenzenesulfonate 
• 131086-39-0 4-benzoylphenyl 4-methylbenzenesulfonate 
• 696-62-8 para-iodoanisole 
• 356031-48-6 4′-methoxy-[1,1′-biphenyl]-4-yl 4-methylbenzenesulfonate 
• 1433269-81-8 4-(2-phenylallyl)phenyl 4-methylbenzenesulfonate 

Relevant academic research and scientific papers

Electrochemical cross-coupling reactions of sodium arenesulfinates with thiophenols and phenols

A green electrochemical oxidative cross-coupling protocol for the generation of thiosulfonates and sulfonate esters using sodium arenesulfinates and thiophenols/phenols is disclosed. The protocol involves using inorganic and non-toxic NaI as both redox catalyst and supporting electrolyte at room temperature without oxidant and base. The reactions provide good yields of products and tolerate broad substrate scope. The mechanistic studies revealed that the reactions proceed via a radical pathway for the formation of SO2–S and SO2–O bonds.

Generation of Organozinc Reagents from Arylsulfonium Salts Using a Nickel Catalyst and Zinc Dust

Readily available aryldimethylsulfonium triflates react with zinc powder under nickel catalysis via the selective cleavage of the sp2-hybridized carbon-sulfur bond to produce salt-free arylzinc triflates under mild conditions. This zincation displays superb chemoselectivity and thus represents a protocol that is complementary or orthogonal to existing methods. The generated arylzinc reagents show both high reactivity and chemoselectivity in palladium-catalyzed and copper-mediated cross-coupling reactions.

Pd-Catalyzed Conversion of Aryl Iodides to Sulfonyl Fluorides Using SO2 Surrogate DABSO and Selectfluor

A one-pot Pd-catalyzed conversion of aryl iodide to aryl sulfonyl fluorides using DABSO and Selectfluor has been developed generating aryl sulfonyl fluorides in good to excellent yields. The reaction results in the generation of electronically and sterically diverse sulfonyl fluorides. Additionally, sulfonyl fluorides can be converted to aryl sulfonamides and sulfonic esters using Cs2CO3 under mild conditions.

Iodine-induced synthesis of sulfonate esters from sodium sulfinates and phenols under mild conditions

An iodine-induced synthesis of sulfonate esters via cross-coupling reactions of sodium sulfinates with phenols is reported. This synthetic route is low-cost, facile, green and efficient, and could afford the target products with good to excellent yields u