80465-16-3Relevant academic research and scientific papers
Electrosynthesis of 1,3,5-trisubstituted 1,2,4-triazoles from phenylhydrazine, aldehydes and amines under mild conditions
Yuan, Ling,Yuan, Gao-Qing
, (2022/01/24)
A simple and convenient method for the electrosynthesis of 1,3,5-trisubstituted 1,2,4-triazoles with three components of phenylhydrazine, aldehydes and amines has been established. The electrolysis could be smoothly carried out at room temperature without additional strong oxidants and catalysts to afford the target product in good yields. This electrochemical route effectively extends synthetic field of 1,2,4-triazole derivatives.
Heterocycles from N-Benzoylthioamides and Dinucleophilic Reagents
Whitfield, Lawrence L.,Papadopoulos, Eleftherios P.
, p. 1197 - 1201 (2007/10/02)
N-Benzoylthioamides (I) react with hydrazines and hydroxylamine to form 1H-1,2,4-triazoles and 1,2,4-oxazoles, respectively.A similar treatment of the S-methyl derivatives of 1 with amidines leads to 1,3,5-triazines.Ethyl N-benzoylthiocarbamate undergoes analogous reactions to yield the corresponding ethoxyheterocycles.
