80485-94-5Relevant academic research and scientific papers
ALKYLATION OF CH ACIDS IN THE PRESENCE OF POTASSIUM CARBONATE. III. ALKYLATION OF CH ACIDS BY 2,3-SUBSTITUTED 1,4-DIBROMO-2-BUTENES
Vardapetyan, A. A.,Khachatryan, D. S.,Morlyan, N. M.
, p. 1237 - 1242 (2007/10/02)
During the cycloalkylation of CH acids by 2,3-substituted (methyl-chlorine) 1,4-dibromo-2-butenes the direction of intramolecular C- and O-alkylation depends both on steric and on electronic factors.The introduction of substituents into the alkylating agent and the presence of acetyl groups in the initial CH acids promote regiospecific intramolecular O-alkylation.
