80504-86-5Relevant academic research and scientific papers
1,3-Butadienyltributylphosphonium Bromide as a Conjunctive Reagent for the Synthesis of 1,3-Dienes from Carbonyl Compounds and Gilman Cuprates
Scheuplein, Stefan W.,Brueckner, Reinhard
, p. 1871 - 1874 (2007/10/02)
A one-pot non-stereoselective synthesis of 1,3-dienes from (4-bromo-2-butenyl)tributylphosphonium bromide (9), Gilman cuprates, and aldehydes or ketones is described.The yields of the dienes reach 79percent or 63percent when aldehydes and ketones are used, respectively.The pentadienylsilane 10k is accessible similarly in 56 percent yield. Key Words: Conjugate addition/ Cuprates/ 1,3-Dienes/ Wittig reaction
METAL COMPLEXES IN ORGANIC SYNTHESIS. VIII. ALLYLIC ALCOHOLS AS STARTING MATERIALS IN PALLADIUM-CATALYZED WITTIG-TYPE OLEFINIZATIONS.
Moreno-Manas,Truis
, p. 2154 - 2158 (2007/10/02)
Allylic alcohols, aldehydes, and triphenylphosphine participate in a one-pot process catalyzed by palladium, which is formally equivalent to the Wittig olefinization. It can be applied to both aliphatic and aromatic aldehydes. The resulting olefins which appear as mixtures of stereoisomers were fully hydrogenated. Two different mechanisms can account for the observed results.
DOUBLE BOND FORMATION BY ONE POT PALLADIUM INDUCED REACTIONS BETWEEN ALDEHYDES, ALLYLIC ALCOHOLS AND TRIPHENYLPHOSPHINE
Moreno-Manas, M.,Trius, A
, p. 3109 - 3112 (2007/10/02)
The reaction between several aldehydes, two allylic alcohols and triphenylphosphine under palladium catalysis leads to double bond formation, synthetically parallelizing the Wittig reaction.
