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3-Bromo-4-methoxyaniline is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical agents. It is characterized by the presence of a bromine atom at the 3-position and a methoxy group at the 4-position on the aniline molecule, which contributes to its reactivity and potential applications in medicinal chemistry.

80523-34-8

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80523-34-8 Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-4-methoxyaniline is used as a key intermediate for the preparation of triazole analogs of combretastatin A-4. These analogs exhibit cytotoxic properties and function as inhibitors of tubulin, playing a significant role in the development of anticancer drugs.
3-Bromo-4-methoxyaniline is also used in the synthesis of (1,2,4-oxadiazolyl)biphenylcarbonyltetrahydrospiro[furo]indolepiperidine (SB-224289), which is a selective 5-HT1B receptor inverse agonist. 3-BROMO-4-METHOXYANILINE has potential applications in the treatment of various neurological and psychiatric disorders, such as migraine, depression, and anxiety, due to its ability to modulate serotonin signaling pathways.

Check Digit Verification of cas no

The CAS Registry Mumber 80523-34-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,5,2 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80523-34:
(7*8)+(6*0)+(5*5)+(4*2)+(3*3)+(2*3)+(1*4)=108
108 % 10 = 8
So 80523-34-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H8BrNO.ClH/c1-10-7-3-2-5(9)4-6(7)8;/h2-4H,9H2,1H3;1H

80523-34-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-bromo-4-methoxyaniline,hydrochloride

1.2 Other means of identification

Product number -
Other names 3-BROMO-4-METHOXYANILINE HYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80523-34-8 SDS

80523-34-8Upstream product

80523-34-8Relevant academic research and scientific papers

NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVING BOTH AROMATIC AND HALOGENIC SUBSTITUENTS

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Paragraph 0621; 0622, (2014/03/24)

Certain 4,6-disubstituted aminopyrimidine derivatives having both aromatic and halogenic substituents.

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