80528-12-7

Basic information

• Product Name: benzyl 4-[(2R)-1-(tert-butyl-dimethylsilyl)-4-oxoazetidin-2-yl)but-2-enoate
• CAS NO: 80528-12-7
• Molecular Weight: 359.541
• Mol File: 80528-12-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl 4-[(2R)-1-(tert-butyl-dimethylsilyl)-4-oxoazetidin-2-yl)but-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 4-[(2R)-1-(tert-butyl-dimethylsilyl)-4-oxoazetidin-2-yl)but-2-enoate(80528-12-7)
• EPA Substance Registry System: benzyl 4-[(2R)-1-(tert-butyl-dimethylsilyl)-4-oxoazetidin-2-yl)but-2-enoate(80528-12-7)

Safety Data

• Hazardous Substances Data: 80528-12-7(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 86833-67-2 N-tert-butyldimethylsilyl-4(R)-allyl-2-azetidinone 
• 82468-77-7 4-allyl-2-azetidinone 
• 82448-89-3 ((R)-1-[1,3]Dithian-2-ylmethyl-but-3-enyl)-carbamic acid 2,2,2-trichloro-ethyl ester 
• 82448-91-7 (R)-3-(2,2,2-Trichloro-ethoxycarbonylamino)-hex-5-enoic acid 
• 82448-90-6 [(R)-1-(2-Oxo-ethyl)-but-3-enyl]-carbamic acid 2,2,2-trichloro-ethyl ester 
• 82448-88-2 (R)-1-[1,3]Dithian-2-ylmethyl-but-3-enylamine 
• 82448-92-8 (R)-3-aminohex-5-enoic acid 

Downstream Products

• 76144-20-2 (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one 

Relevant articles and documents

4-Substituted-2-oxoazetidine compounds

The present invention relates to novel 4-substituted-2-oxoazetidine compounds and to processes for preparing the same. These compounds are useful intermediates for preparing antibiotics having the basic skeleton of Thienamycin.

AN ENANTIOSELECTIVE ROUTE TO AN INTERMEDIATE OF THE CARBAPENAM SYSTEM FROM THE CHIRAL γ-BUTYROLACTONE

A new enantioselective synthesis of the keto ester(16) containing β-lactam ring system has been developed using the chiral lactone(1) as a starting material.