80530-55-8Relevant articles and documents
N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases
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, (2008/06/13)
The present invention describes compounds of formula I and enantiomers, diastereomers and pharmaceutically acceptable salts thereof. The formula I compounds are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for examp
A process for the production of benzene derivatives
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, (2008/06/13)
The present invention relates to a process for the production of benzene derivatives as compounds of chemical formula ( I ) below which are used as intermediates of agricultural chemical, fine chemical products or pharmaceuticals such as anti inflammatory analgesics. The process for the production of benzene derivatives of present invention expressed in below chemical formula ( I ) is characterized by making reaction between compound of chemical formula ( II ) and hydrofomylating agent under halogenation agent. In chemical formula ( I ) and ( II ), X is halogenic atom, R1& R2are same or different each other, R1is hydrogen atom or low alkyl radical of carbon number 1 ~ 6, R2is hydrogen atom or COOR3, and R3is hydrogen atom or low alkyl radical of carbon number 1 ~ 6.