805316-71-6

Basic information

• Product Name: 2,6-DICHLORO-N4-METHYLPYRIDINE-3,4,5-TRIAMINE
• Synonyms: 2,6-DICHLORO-N4-METHYLPYRIDINE-3,4,5-TRIAMINE
• CAS NO: 805316-71-6
• Molecular Formula: C6H8Cl2N4
• Molecular Weight: 207.063
• Mol File: 805316-71-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-DICHLORO-N4-METHYLPYRIDINE-3,4,5-TRIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORO-N4-METHYLPYRIDINE-3,4,5-TRIAMINE(805316-71-6)
• EPA Substance Registry System: 2,6-DICHLORO-N4-METHYLPYRIDINE-3,4,5-TRIAMINE(805316-71-6)

Safety Data

• Hazardous Substances Data: 805316-71-6(Hazardous Substances Data)

Usage

Type of compound

Nitrification inhibitor

Usage

Used in agriculture to slow down the conversion of ammonium into nitrate in soil

Function

Inhibits the activity of ammonia-oxidizing bacteria, allowing plants more time to uptake essential nutrients

Application

Commonly applied to soils as a liquid or granular form

Effectiveness

Particularly effective in reducing nitrogen losses in high nitrogen input systems, such as those used for corn or wheat production

Precautions

Toxic to aquatic organisms and can cause skin and eye irritation in humans, handle and apply with caution.

Upstream product

• 10425-70-4 4-chloro-3,5-dinitropyridine 
• 26820-38-2 (3,5-dinitropyridin-4-yl)methylamine 
• 19872-96-9 1H-3,5-dinitropyridine-4-one 
• 626-64-2 pyridin-4-ol 

Downstream Products

• 914942-88-4 tert-butyl (6-amino-7-iodo-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)(methyl)carbamate 
• 887147-21-9 4-methylamino-6-chloro-1-methyl-1H-imidazo[4,5-c]pyridine 
• 887147-19-5 4,6-dichloro-1-methyl-1H-imidazo [4,5-c]pyridine 
• 805316-72-7 7-amino-4,6-dichloro-1-methyl-1H-imidazo[4,5-c]pyridine 

Relevant articles and documents

Novel tricyclic inhibitors of 1κB kinase

The design and synthesis of a novel series of oxazole-, thiazole-, and imidazole-based inhibitors of IκB kinase (IKK) are reported. Biological activity was improved compared to the pyrazolopurine lead, and the expedient synthesis of the new tricyclic systems allowed for efficient exploration of structure-activity relationships. This, combined with an iterative rat cassette dosing strategy, was used to identify compounds with improved pharmacokinetic (PK) profiles to advance for in vivo evaluation.

1H-IMIDAZO[4,5-D]THIENO[3,2-B]PYRIDINE BASED TRICYCLC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

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Imidazo-fused oxazolo[4,5-b]pyridine and imidazo-fused thiazolo[4,5-b]pyridine based tricyclic compounds and pharmaceutical compositions comprising same

The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.