805323-20-0Relevant articles and documents
LiCl-mediated preparation of highly functionalized benzylic zinc chlorides
Metzger, Albrecht,Schade, Matthias A.,Knochel, Paul
supporting information; experimental part, p. 1107 - 1110 (2009/04/06)
In the presence of zinc dust (1.5-2.0 equiv) and LiCI(1.5-2.0 equiv), various benzylic chlorides bearing functional groups (iodide, cyanide, ester, ketone) are smoothly converted at 25°C to the corresponding zinc reagents without homo-coupling (≤5%). The utility of these benzylic zinc reagents is demonstrated by a short synthesis of papaverine.
Transformation of (+)-thiomicamine into a new ligand for the enantioselective addition of methyllithium to prochiral imines
Broezda, Danuta,Chrzanowska, Maria,Glaszynska, Agata,Rozwadowska, Maria D.
, p. 4791 - 4796 (2007/10/03)
A new ligand 2 was prepared from (+)-thiomicamine 1 and o-methoxyphenol, and its activity as an external controller of stereochemistry in enantioselective additions of methyllithium to prochiral imines 8-10 tested. The non-racemic secondary amines 11-13 w
5, 10-Dihydroimidazo[2,1-b]quinazolines and pharmaceutical compositions containing them
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, (2008/06/13)
A 5,10-dihydroimidazo[2,1-b]quinazoline in which at least one ring carbon atom, other than the carbon atom in the 2-position, bears a substituent, or a pharmaceutically acceptable acid addition salt thereof is a useful cardiotonic agent and vasodilator in heart insufficiency and a blood platelet aggregation inhibitor.