80536-99-8 Usage
Uses
Used in Pharmaceutical Industry:
PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID HYDRAZIDE is used as a potential antitumor agent for its ability to inhibit the activity of the tumor necrosis factor (TNF) alpha, a protein involved in inflammation and immune system response. This makes it a candidate for treating various types of cancers.
Used in Cancer Research:
PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID HYDRAZIDE is used as a subject of ongoing research to understand its mechanism of action and explore its potential applications in the field of cancer treatment. It has been studied for its potential therapeutic use in treating cancers such as breast cancer, leukemia, and lymphoma.
Check Digit Verification of cas no
The CAS Registry Mumber 80536-99-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,5,3 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 80536-99:
(7*8)+(6*0)+(5*5)+(4*3)+(3*6)+(2*9)+(1*9)=138
138 % 10 = 8
So 80536-99-8 is a valid CAS Registry Number.
80536-99-8Relevant academic research and scientific papers
HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS
-
Paragraph 0756; 0757, (2018/06/12)
Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
1,3-Dipolar Addition of Pyridine N-Imine to Acetylenes and the Use of C-13 NMR in Several Structural Assignments
Anderson, Paul L.,Hasak, James P,Kahle, Alicia D.,Paolella, Nicholas A.,Shapiro, Michael J.
, p. 1149 - 1152 (2007/10/02)
Addition of pyridine-N-imine to a variety of acetylenic mono- (Scheme I) and di- (Scheme II) carboxylic ester dipolarophiles was carried out.Several of the 3-azapyrrocoline esters obtained were further converted into acids, amides and hydrazides as shown in Schemes I and II.
