16205-44-0

Basic information

• Product Name: ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE
• Synonyms: ETHYL PYRAZOLO[1,5-A]PYRIDINE-3,4-CARBOXYLATE;ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE;EthylH-pyrazolo[1,5-a]pyridine-3-carboxylate;Ethyl pyrazolo[1,5-a]pyri...;3-(Ethoxycarbonyl)pyrazolo[1,5-a]pyridine;Ethyl 1H-pyrazolo[1,5-a]pyridine-3-carboxylate
• CAS NO: 16205-44-0
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.2
• Product Categories: Heterocycle-Pyridine series
• Mol File: 16205-44-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 134-135°C/3mm
• Flash Point: 134-135°C/2.3mm
• Appearance: /
• Density: 1.23
• Refractive Index: 1.5800
• Storage Temp.: 2-8°C
• PKA: 0.68±0.30(Predicted)
• CAS DataBase Reference: ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE(16205-44-0)
• EPA Substance Registry System: ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE(16205-44-0)

Safety Data

• Hazard Codes: Xi
• Statements: 22-36/37/38
• Safety Statements: 23-26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 16205-44-0(Hazardous Substances Data)

Usage

General Description

Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate is a chemical compound with the molecular formula C11H9N3O2. It is a carboxylic ester derivative of pyrazolo[1,5-a]pyridine-3-carboxylic acid, and it is commonly used in pharmaceutical research and development. ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE has shown potential as a building block for the synthesis of various bioactive molecules and pharmaceutical drugs. Its structure and properties make it a valuable tool for medicinal chemistry and drug discovery efforts. Additionally, the ester group in ethyl pyrazolo[1,5-a]pyridine-3-carboxylate also make it a versatile precursor for the synthesis of other pyrazolo[1,5-a]pyridine derivatives with potential biological activities.

InChI:InChI=1/C10H10N2O2/c1-2-14-10(13)8-7-11-12-6-4-3-5-9(8)12/h3-7H,2H2,1H3

Upstream product

• 5459-35-8 2-bromo-acrylic acid ethyl ester 
• 39996-41-3 1-aminopyridinium mesitylenesulphonate 
• 45458-31-9 N-Aminopyridinium 
• 623-47-2 propynoic acid ethyl ester 
• 6295-87-0 N-aminopyridin-1-ium iodide 
• 105-37-3 Ethyl propionate 
• 140-88-5 ethyl acrylate 

Downstream Products

• 221470-50-4 FAUC 113 
• 362661-83-4 pyrazolo[1,5-a]pyridine-7-carboxaldehyde 
• 16205-46-2 pyrazolo[1,5-a]pyridine-3-carboxylic acid 
• 25627-89-8 pyrazolo[1,5-a]pyridine-3-carbonitrile 
• 73957-66-1 3-pyrazolo<1,5-a>pyridineacarboxaldehyde 
• 117782-76-0 3-(hydroxymethyl)pyrazolo<1,5-a>pyridine 
• 80536-99-8 pyrazolo<1,5-a>pyridine-3-carboxhydrazide 
• 118055-06-4 4,5,6,7-Tetrahydropyrazolo<1,5-a>pyridin-3-carbonsaeureethylester 
• 221470-47-9 3-(4-phenylpiperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine 
• 19363-97-4 1-nitropyrazolo<5,1-a>pyridine 

Relevant articles and documents

Synthesis, characterization, optical properties, computational characterizations, QTAIM analysis and cyclic voltammetry of new organic dyes for dye-sensitized solar cells

In recent years, dye-sensitized solar cells (DSSCs) have regarded as potential solar cells for the next generation of photovoltaic technologies. Many organic compounds are explored and used in DSSCs to produce low-cost devices and improve the cell efficiency. In this work, three new heterocyclic purple dyes are synthesized from the reaction of 3-nitropyrazolo[1,5-a]pyridine with various arylacetonitriles for dye-sensitized solar cells (DSSCs), exhibiting high molar extinction coefficients and a broad absorption range led to the good photovoltaic performance of 6.95–7.18%. Physical spectral, analytical data and optical properties are established the structures of the new dyes. The optimized geometries and relevant frontier orbitals of the dyes are obtained by density functional theory (DFT) at the level of B3LYP/6-311 + G(d,p). Electrostatic potential maps and electron density maps of the dyes were also obtained by atoms in molecules (AIM) analysis. Cyclic voltammetry measurement was performed to evaluate the electrochemical properties of the dyes and reversible oxidation waves were observed for them.

Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties

Tumor-associated macrophages (TAMs) are predominantly associated with tumor growth. Colony-stimulating factor 1 receptor (CSF1R) acts as a key regulator of TAM survival and differentiation and is a molecular target for cancer therapies. Herein, novel CSF1

Azacycle diketone compound and preparation method thereof (by machine translation)

The invention provides a azacyclodiketone compound which is characterized by being a compound represented by the following structure. The compound has inhibitory activity on cap-dependent endonuclease. (by machine translation)