80538-49-4

Basic information

• Product Name: ethyl (1E)-N-(benzoyloxy)ethanimidoate
• CAS NO: 80538-49-4
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.2258
• Mol File: 80538-49-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 277.427°C at 760 mmHg
• Flash Point: 112.87°C
• Density: 1.066g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: ethyl (1E)-N-(benzoyloxy)ethanimidoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (1E)-N-(benzoyloxy)ethanimidoate(80538-49-4)
• EPA Substance Registry System: ethyl (1E)-N-(benzoyloxy)ethanimidoate(80538-49-4)

Safety Data

• Hazardous Substances Data: 80538-49-4(Hazardous Substances Data)

Upstream product

• 10576-12-2 ethyl acetohydroximate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 613-46-7 2-naphthalenecarbonitrile 
• 54495-98-6 O-Benzoylhydroxylamine 

Relevant articles and documents

Direct and Catalytic Amide Synthesis from Ketones via Transoximation and Beckmann Rearrangement under Mild Conditions

The Br?nsted acid-catalyzed synthesis of secondary amides from ketones under mild conditions is described via transoximation and Beckmann rearrangement using O-protected oximes as more stable equivalents of explosive O-protected hydroxylamines. This methodology could be applied to highly rearrangement-selective amide synthesis from α-branched alkyl aryl ketones and performed on a 1-g scale. The presence of water is essential for this reaction, and its role was clarified by isotope-labeling experiments.