80541-53-3Relevant academic research and scientific papers
Dimerisation of Indolizines by Palladium Coal
Kreher, Thomas,Sonnenschein, Helmut,Schmidt, Lothar,Huenig, Siegfried
, p. 1173 - 1176 (2007/10/02)
Oxidative dimerisation of some indolizines by Pd/C in p-xylene was undertaken in order to evaluate reaction conditions for cyclophane syntheses.Surprisingly, alkylation by the solvent occurred at the 3-position of the indolizines 2 and 5 as a side reaction.In toluene, yields of alkylation products 4b and 8 exceeded those of dimerisation products 3 and 6.The alkylation by the solvent was fully suppressed by using chlorobenzene and chlorotoluene.Alkylation products of indolizines with p-xylene or toluene and previously unknown dimeric indolizines are described. - Key Words: Indolizines / Oxidative dimerisation, palladium-promoted / Cyclophanes
Facile Dehydrogenative Dimerization of Indolizine Derivatives
Kakehi, Akikazu,Ito, Suketaka,Hamaguchi, Akihiro,Okano, Tsutomu
, p. 2833 - 2834 (2007/10/02)
Treatment of 3-unsubstituted indolizines with a dehydrogenating agent such as palladium on carbon in refluxing xylene gave the corresponding 3,3'-biindolizine derivatives in 19-74percent yields.
