80543-51-7

Basic information

• Product Name: O-FORMYLMANDELOYL CHLORIDE
• Synonyms: S-FMOC
• CAS NO: 80543-51-7
• Molecular Formula: C₉H₇ClO₃
• Molecular Weight: 198.6
• Mol File: 80543-51-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 267.2±33.0 °C(Predicted)
• Appearance: /
• Density: 1.309±0.06 g/cm3(Predicted)
• CAS DataBase Reference: O-FORMYLMANDELOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: O-FORMYLMANDELOYL CHLORIDE(80543-51-7)
• EPA Substance Registry System: O-FORMYLMANDELOYL CHLORIDE(80543-51-7)

Safety Data

• Hazardous Substances Data: 80543-51-7(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 17199-29-0 (S)-Mandelic acid 
• 95107-08-7 (S)-formyloxy(phenyl)acetic acid 

Downstream Products

• 42540-40-9 cefamandole nafate 
• 42540-40-9 Bergacef 
• 52775-40-3 (6R)-7t-((Ξ)-2-hydroxy-2-phenyl-acetylamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 95271-97-9 4-nitrobenzyl (2'S,6R,7R)-3-acetoxymethyl-7-hydroxy(phenyl)acetylaminoceph-3-em-4-carboxylate 
• 95107-28-1 4-nitrobenzyl (5'S,6R,7S)-3-acetoxymethyl-4'-oxo-5'-phenylspiro(1',3'-oxazolidine-2',7-ceph-3-em)-4-carboxylate 
• 95107-15-6 4-nitrobenzyl (3S,5'S,5R,6S)-4'-oxo-5'-phenylspiro(1',3'-oxazolidine-2',6-penicillanate) 
• 95107-13-4 4-nitrobenzyl (2'S,3S,5R,6R)-6-hydroxy(phenyl)acetylaminopenicillanate 
• 95107-29-2 (5'S,6R,7S)-3-acetoxymethyl-4'-oxo-5'-phenylspiro(1',3'-oxazolidine 2',7-ceph-3-em)-4-carboxylic acid 
• 95107-16-7 (3S,5'S,5R,6S)-4'-oxo-5'-phenylspiro(1',3'-oxazolidine-2',6-penicillanic acid) 
• 24008-64-8 (2'S,3S,5R,6R)-6-hydroxy(phenyl)acetylaminopenicillanic acid 
• 95107-30-5 (6R,7R,2'S)-3-acetoxymethyl-7-hydroxy(phenyl)acetylaminoceph-3-em-4-carboxylic acid 
• 95107-22-5 4-nitrobenzyl (2'S,6R,7S)-7-formyloxy(phenyl)acetylamino-7-methylthio-3-methylceph-3-em-4-carboxylate 
• 95107-10-1 (2'S,3S,5R,6R)-6-formyloxy(phenyl)acetylaminopenicillanic acid 
• 62352-28-7 (6R)-7t-((Ξ)-2-formyloxy-2-phenyl-acetylamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Relevant articles and documents

Synthetic method of L-type cefamandole nafate

The invention provides a synthesis method of L-type cefamandole nafate, which comprises the following steps of carrying out silanization reaction on 7-ATCA and a silane protective agent in the presence of an organic solvent, carrying out acylation reaction with L-formyl mandelic acid chloride, removing silane protective groups, carrying out salification reaction with a sodium salt solution, and carrying out freeze drying to obtain an L-type cefamandole nafate solid. The invention provides an efficient and simple synthetic method of L-type cefamandole nafate.