80563-98-0

Usage

Spiro compound family

Yes
A spiro compound is characterized by a carbon atom connected to two non-adjacent atoms through single bonds, forming a spiro center.

Contains two sulfur atoms

Yes
The compound has two sulfur atoms in its structure, which contribute to its unique properties and reactivity.

Cyclic structure

Yes
The compound has a closed ring structure, which is a common feature in many organic compounds.

Used in organic synthesis

Yes
1,4-Dithiaspiro[4.5]decan-7-one is utilized as a building block or intermediate in the synthesis of various organic compounds.

Building block in pharmaceuticals and fine chemicals

Yes
Due to its unique structure and reactivity, the compound is used in the production of pharmaceuticals and fine chemicals.

Potential applications in materials science

Yes
The compound's properties may be exploited in the development of new materials with specific characteristics.

Potential applications in drug discovery

Yes
The compound's unique structure and reactivity make it a candidate for use in the development of new drugs and therapeutic agents.

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 65225-59-4 2-ethoxy-[1,3]dithiolane 
• 540-63-6 ethane-1,2-dithiol 
• 7490-36-0 1,4,8,11-tetrathia-dispiro[4.1.4.3]tetradecane 

Downstream Products

• 128441-13-4 1,4-dithiaspiro<4.5>decan-7-ol 

Relevant academic research and scientific papers

Ring-opening reactions of donor-acceptor cyclopropanes with cyclic ketals and thiol ketals

1,3-Cyclohexandione derived cyclic ketals and thiol ketals were used as O- and S-nucleophiles, respectively, for the ring opening of donor-acceptor cyclopropanes catalyzed by Cu(OTf)2 and a series of functionalized alkylene glycol diethers and dithiol diethers were obtained in good to high yields under mild conditions. This journal is

Studies on the selective hydrolysis of bis-dithiolanes with cerric ammonium nitrate: synthesis of 1,4-dithiaspirodecan-7-ones

Dimedone 10 is directly ketalised with ethanedithiol to bis dithiolane 11 using Dean-Stark conditions.The selective hydrolysis of bis-dithiolane 11 to the ketodithiolane 12 employing cerric ammonium nitrate (CAN) proceeds in 35percent yield under optimal conditions.A few examples are reported.

The substrate- and stereoselectivity of microbial reductions of 1,4-dithiaspirodecanones and 1,5-dithiaspiroundecanones

The title spirocyclic ketones, possessing possible substitution patterns 1,4-dithiaspirodecan-6-one (1a), -7-one (3a), and -8-one (5a) and 1,5-dithiaspiroundecan-7-one (2a), -8-one (4a), and -9-one (6a), have been reduced with new strains of yeast (Saccharomyces cerevisiae, JCM 1819 and JCM 2214).Reductions of the prochiral ketones 1a-4a occur with high enantiofacial selectivity on the preparative scale (up to 99percent ee).The product alcohols (1,4-dithiaspirodecan-6-ol (1b) and -7-ol (3b) and 1,5-dithiaspiroundecan-7-ol (2b) and -8-ol (4b)) have theS configuration, as confirmed by 2D COSY experiments of the (S)-MTPA ester of 1b-4b using the configuration correlation model of Mosher.

The Reaction of 2-Ethoxy-1,3-oxathiolane with Carbonyl Compounds in the Presence of ZnCl2 or HgCl2

In the reaction of 2-ethoxy-1,3-oxathiolane with carbonyl compounds in the presence of ZnCl2 or HgCl2, it has been found that only the breaking of the endocyclic bond (C-O or C-S bond) occurs, while the breaking of the exocyclic C-O bond to give the 1,3-o