80567-69-7

Upstream product

• 79-11-8 chloroacetic acid 
• 2687-25-4 3-methyl-1,2-benzenediamine 

Downstream Products

• 122500-95-2 8-Methyl-4-phenyl-1H-2-oxa-3,4a,9-triaza-fluorene 
• 122501-07-9 (2-Chloromethyl-4-methyl-benzoimidazol-1-yl)-(4-nitro-phenyl)-methanone oxime 
• 122500-92-9 (2-Chloromethyl-4-methyl-benzoimidazol-1-yl)-phenyl-methanone oxime 
• 122501-04-6 (2-Chloromethyl-4-methyl-benzoimidazol-1-yl)-p-tolyl-methanone oxime 
• 122501-05-7 (2-Chloromethyl-4-methyl-benzoimidazol-1-yl)-(2-chloro-phenyl)-methanone oxime 
• 122501-06-8 (2-Chloromethyl-4-methyl-benzoimidazol-1-yl)-(4-chloro-phenyl)-methanone oxime 

Relevant academic research and scientific papers

NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS

The present invention disclosed a novel EGFR inhibitor compound of formula (I), process for preparation thereof and methods of treating abnormal cell growth in mammals by administering the compounds of formula (I). Wherein, R= -H, 3-CH3, 4-NO2, 4-Cl, 2-CH3, 4-CH3, 4-Br, 4-F R1= -H, -4-OCH3, -4-NO2,-2-NO2, -4-Cl, -2,4,6-CH3, -4-CH3, -2-F,4-Br, -4-CF3, -4-S-CH3, -4-Cl,-3-CF3, -3-S-CH3, -3,5-CF3, -2-S-CH3, -3-CF3,-4-OCF3, -Si-(CH3)3, -Si-(C2H5)3, (CH3)2-Si- C2H5.

2-(4-pyridylaminomethyl)-benzimidazole derivatives having antiviral activity

Provided herein is an antiviral 2-(4-pyridylaminomethyl)-benzimidazole of the formula: STR1 wherein R is a radical selected from the groups consisting of hydrogen, short-chain alkyl, short-chain alkoxy, benzoyl, halogenomethyl, halogen, nitro and amino groups; the preparation of these compounds and antiviral composition containing such compounds.