80568-01-0

Basic information

• Product Name: 1-{[2-(diethylamino)ethyl]amino}-4-nitro-9H-thioxanthen-9-one
• Synonyms: 1-((2-(Diethylamino)ethyl)amino)-4-nitro-9H-thioxanthen-9-one; 9H-thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-nitro-
• CAS NO: 80568-01-0
• Molecular Formula: C₁₉H₂₁N₃O₃S
• Molecular Weight: 371.4533
• Mol File: 80568-01-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 561.7°C at 760 mmHg
• Flash Point: 293.5°C
• Density: 1.311g/cm³
• Vapor Pressure: 1.2E-12mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 1-{[2-(diethylamino)ethyl]amino}-4-nitro-9H-thioxanthen-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[2-(diethylamino)ethyl]amino}-4-nitro-9H-thioxanthen-9-one(80568-01-0)
• EPA Substance Registry System: 1-{[2-(diethylamino)ethyl]amino}-4-nitro-9H-thioxanthen-9-one(80568-01-0)

Safety Data

• Hazardous Substances Data: 80568-01-0(Hazardous Substances Data)

Usage

Type of Compound

Fluorescent dye

Application

Used in biological and medical research

Specific Use

Stains amyloid deposits in tissue samples for easier identification under a microscope

Potential Use

Treatment and diagnosis of neurodegenerative diseases (e.g., Alzheimer's disease and Parkinson's disease)

Mechanism of Action

Binds to and inhibits the aggregation of certain proteins associated with neurodegenerative diseases

Chemical Structure

Unique structure that contributes to its properties and applications

Scientific and Medical Applications

Valuable tool in various research and diagnostic processes due to its specific properties and interactions with proteins

Upstream product

• 41215-88-7 1-chloro-4-nitrothioxanthenone 
• 100-36-7 N,N-diethylethylenediamine 

Downstream Products

• 80568-02-1 4-amino-1-<<2-(diethylamino)ethyl>amino>thioxanthenone 

Relevant articles and documents

Nitro and Amino Derivatives of Lucanthone as Antitumor Agents

A group of nitro and amino derivatives of lucanthone was prepared and tested for antitumor activity.Reaction of 1-chloro-4-methyl-7-nitrothioxanthenone and N,N-diethylethylenediamine gave 7-amino analogue (11) directly, accompanied by 7-amino-1-chloro-4-m